1.14.13.127: 3-(3-hydroxyphenyl)propanoate hydroxylase

This is an abbreviated version!
For detailed information about 3-(3-hydroxyphenyl)propanoate hydroxylase, go to the full flat file.

Reaction

Synonyms

3-(3-hydroxyphenyl)propionate hydroxylase, 3HPP 2-hydroxylase, 3HPP hydroxylase, MhpA, MhpAK-12

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase

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Results	in table
2172	AA Sequence
1	Cloned(Commentary)
9	Cofactor
1	Expression
8	General Information
2	kcat/KM [mM/s]
2	KM Value [mM]
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
13	Organism
7	Pathway
1	pH Optimum
2	Protein Variants
1	Purification (Commentary)
2	Reaction
11	Reference
2	Specific Activity [micromol/min/mg]
13	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.14.13.127 - 3-(3-hydroxyphenyl)propanoate hydroxylase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+

2 entries

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O

4 entries

3-(3-hydroxyphenyl)propanoate + NADPH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NADP+

2 entries

additional information

?

-

4 entries

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+

Escherichia coli

P77397

-

763969

-

-

?

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+

Escherichia coli W3110

P77397

-

763969

-

-

?

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O

Comamonas testosteroni

-

-

716131

-

-

ir

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O

Comamonas testosteroni TA441

-

-

716131

-

-

ir

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O

Escherichia coli

-

-

659003, 659007, 715333

-

-

?

3-(3-hydroxyphenyl)propanoate + NADH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O

Escherichia coli KK334

-

-

659003

-

-

?

3-(3-hydroxyphenyl)propanoate + NADPH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NADP+

Escherichia coli

P77397

-

763969

-

-

?

3-(3-hydroxyphenyl)propanoate + NADPH + H+ + O2

3-(2,3-dihydroxyphenyl)propanoate + H2O + NADP+

Escherichia coli W3110

P77397

-

763969

-

-

?

additional information

?

-

Escherichia coli

-

MhpA does not oxidize melilotate

715333

-

-

?

additional information

?

-

Escherichia coli

P77397

substrate and product identification by mass spectrometry

763969

-

-

-

additional information

?

-

Escherichia coli

-

substrate and product identification by mass spectrometry

763969

-

-

-

additional information

?

-

Escherichia coli W3110

P77397

substrate and product identification by mass spectrometry

763969

-

-

-