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1.14.13.146: taxoid 14beta-hydroxylase

This is an abbreviated version!
For detailed information about taxoid 14beta-hydroxylase, go to the full flat file.

Reaction

10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate
+
O2
+
NADPH
+
H+
=
10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate
+
NADP+
+
H2O

Synonyms

cytochrome P450 taxoid 14beta-hydroxylase, taxoid 14beta-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.146 taxoid 14beta-hydroxylase

Cloned

Cloned on EC 1.14.13.146 - taxoid 14beta-hydroxylase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Saccharomyces cerevisiae WAT11 cells
expressed in the Taxus x media TM3 cell line. The expression of endogenous taxoid 14beta-hydroxylase gene is significantly suppressed by the exogenous as taxoid 14beta-hydroxylase gene
-