1.14.13.23: 3-hydroxybenzoate 4-monooxygenase
This is an abbreviated version!
For detailed information about 3-hydroxybenzoate 4-monooxygenase, go to the full flat file.
Word Map on EC 1.14.13.23
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1.14.13.23
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phenol
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4-hydroxybenzoate
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hydroxylases
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testosteroni
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fad
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gentisate
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comamonas
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mobility-shift
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salicylate
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repressor
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regioselective
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flavoprotein
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unbound
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mobr
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dioxygenase
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protocatechuate
- 1.14.13.23
- phenol
- 4-hydroxybenzoate
- hydroxylases
- testosteroni
- fad
- gentisate
-
comamonas
-
mobility-shift
- salicylate
- repressor
-
regioselective
- flavoprotein
-
unbound
- mobr
- dioxygenase
- protocatechuate
Reaction
Synonyms
3-hydroxybenzoate 4-hydroxylase, 3-hydroxybenzoate hydroxylase, 3-hydroxybenzoate-4-hydroxylase, 3HB4H, EC 1.14.99.13, FAD-dependent 4-hydroxybenzoate hydroxylase, m-hydroxybenzoate hydroxylase, MHBH, MobA, oxygenase, 3-hydroxybenzoate 4-mono-
ECTree
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Inhibitors
Inhibitors on EC 1.14.13.23 - 3-hydroxybenzoate 4-monooxygenase
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4-hydroxy-3-iodomethylbenzoate
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inhibition not reversed in presence of dithiotreitol
MobR
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a 42 kDa dimeric transcriptional regulator of the MarR family, encoded by an open reading frame mobR in the upstream region of mobA, binds to the target DNA and negatively regulates the expression of mobA, the repression is relieved by binding of 3-hydroxybenzoate, binding kinetics, overview
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additional information
MobR from Comamonas testosteroni KH122-3s is a member of the MarR family of transcriptional regulators, binds to DNA, and functions as a repressor for the mobA gene, that encodes a 3-hydroxybenzoate 4-hydroxylase, MobR is inactivated at a high concentration of 2,5-dihydroxybenzoate, 2,3-dihydroxybenzoate, 3-hydroxybenzoate and 3,5-dihydroxybenzoate
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