Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.13.29: 4-nitrophenol 2-monooxygenase

This is an abbreviated version!
For detailed information about 4-nitrophenol 2-monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.29

Reaction

4-nitrophenol
+
NADH
+
H+
+
O2
=
4-nitrocatechol
+
NAD+
+
H2O

Synonyms

4-nitrophenol 4-monooxygenase/4-nitrocatechol 2-monooxygenase, 4-nitrophenol hydroxylase, 4-nitrophenol-2-hydroxylase, 4-NPH, CYP 2E1, CYP2A/2E1, CYP2E1, cytochrome P-450 2E1, cytochrome P-450 isozyme 3a, NphA1, oxygenase, 4-nitrophenol 2-mono-, p-nitrophenol 2-hydroxylase, p-nitrophenol hydroxylase, p-nitrophenol hydroxylase component A, p-nitrophenol-hydroxylase, PNP 2-monooxygenase, PNP monooxygenase, PnpA1, PNPH, PPH, two-component 4-nitrophenol hydroxylase, two-component PNP monooxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.29 4-nitrophenol 2-monooxygenase

Reference

Reference on EC 1.14.13.29 - 4-nitrophenol 2-monooxygenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mitra, D.; Vaidyanathan, C.S.
A new 4-nitrophenol 2-hydroxylase from a Nocardia sp
Biochem. Int.
8
609-615
1984
Nocardia sp.
Manually annotated by BRENDA team
Koop, D.R.
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
Mol. Pharmacol.
29
399-404
1986
Oryctolagus cuniculus
Manually annotated by BRENDA team
Arinc, E.; Aydan, A.
Lung microsomal p-nitrophenol hydroxylase - characterization and reconstitution of its activity
Comp. Biochem. Physiol. B
97
455-460
1990
Ovis aries
Manually annotated by BRENDA team
Reinke, L.A.; Moyer, M.J.
p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol
Drug Metab. Dispos.
13
548-552
1985
Rattus norvegicus
Manually annotated by BRENDA team
Allis, J.W.; Robinson, B.L.
A kinetic assay for p-nitrophenyl hydroxylase in rat liver microsomes
Anal. Biochem.
219
49-52
1994
Rattus norvegicus
Manually annotated by BRENDA team
Hanioka, N.; Watanabe, K.; Yoda, R.; Ando, M.
Effect of alachlor on hepatic cytochrome P 450 enzymes in rats
Drug Chem. Toxicol.
25
25-37
2002
Rattus norvegicus
Manually annotated by BRENDA team
Tassaneeyakul, W.; Veronese, M.E.; Birkett, D.J.; Gonzalez, F.J.; Miners, J.O.
Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
Biochem. Pharmacol.
46
1975-1981
1993
Homo sapiens
Manually annotated by BRENDA team
Vences-Mejia, A.; Labra-Ruiz, N.; Hernandez-Martinez, N.; Dorado-Gonzalez, V.; Gomez-Garduno, J.; Perez-Lopez, I.; Nosti-Palacios, R.; Camacho Carranza, R.; Espinosa-Aguirre, J.J.
The effect of aspartame on rat brain xenobiotic-metabolizing enzymes
Hum. Exp. Toxicol.
25
453-459
2006
Rattus norvegicus
Manually annotated by BRENDA team
Pakala, S.B.; Gorla, P.; Pinjari, A.B.; Krovidi, R.K.; Baru, R.; Yanamandra, M.; Merrick, M.; Siddavattam, D.
Biodegradation of methyl parathion and p-nitrophenol: Evidence for the presence of a p-nitrophenol 2-hydroxylase in a Gram-negative Serratia sp. strain DS001
Appl. Microbiol. Biotechnol.
73
1452-1462
2007
Serratia sp. DS001
Manually annotated by BRENDA team
Zamaratskaia, G.; Zlabek, V.; Chen, G.; Madej, A.
Modulation of porcine cytochrome P450 enzyme activities by surgical castration and immunocastration
Animal
3
1124-1132
2009
Sus scrofa
Manually annotated by BRENDA team
Carvalho, R.S.; Friedrich, K.; De-Oliveira, A.C.; Suarez-Kurtz, G.; Paumgartten, F.J.
Malaria downmodulates mRNA expression and catalytic activities of CYP1A2, 2E1 and 3A11 in mouse liver
Eur. J. Pharmacol.
616
265-269
2009
Mus musculus
Manually annotated by BRENDA team
Takeo, M.; Murakami, M.; Niihara, S.; Yamamoto, K.; Nishimura, M.; Kato, D.; Negoro, S.
Mechanism of 4-nitrophenol oxidation in Rhodococcus sp. Strain PN1: characterization of the two-component 4-nitrophenol hydroxylase and regulation of its expression
J. Bacteriol.
190
7367-7374
2008
Rhodococcus sp. PN1 (Q8RQQ0)
Manually annotated by BRENDA team
Wagner, L.; Zlabek, V.; Trattner, S.; Zamaratskaia, G.
In vitro inhibition of 7-ethoxyresorufin-O-deethylase (EROD) and p-nitrophenol hydroxylase (PNPH) activities by sesamin in hepatic microsomes from two fish species
Mol. Biol. Rep.
40
457-462
2013
Cyprinus carpio, Salmo salar
Manually annotated by BRENDA team
Min, J.; Zhang, J.J.; Zhou, N.Y.
The gene cluster for para-nitrophenol catabolism is responsible for 2-chloro-4-nitrophenol degradation in Burkholderia sp. strain SJ98
Appl. Environ. Microbiol.
80
6212-6222
2014
Rhodococcus opacus, Rhodococcus opacus RKJ300
Manually annotated by BRENDA team
Kallubai, M.; Amineni, U.; Mallavarapu, M.; Kadiyala, V.
In silico approach to support that p-nitrophenol monooxygenase from Arthrobacter sp. strain JS443 catalyzes the initial two sequential monooxygenations
Interdiscip. Sci.
7
157-167
2015
Arthrobacter sp. JS443
Manually annotated by BRENDA team
Kallubai, M.; Amineni, U.; Mallavarapu, M.; Kadiyala, V.
In silico approach to support that p-nitrophenol monooxygenase from Arthrobacter sp. strain JS443 catalyzes the initial two sequential monooxygenations
Interdiscip. Sci. Comput. Life Sci.
7
157-167
2015
Lysinibacillus sphaericus, Arthrobacter sp. (A7YVV2), Arthrobacter sp., Lysinibacillus sphaericus JS905
Manually annotated by BRENDA team
Guo, Y.; Li, D.F.; Zheng, J.; Xu, Y.; Zhou, N.Y.
Single-component and two-component para-nitrophenol monooxygenases structural basis for their catalytic difference
Appl. Environ. Microbiol.
87
e0117121
2021
Rhodococcus opacus, Rhodococcus opacus JCM 13270, Rhodococcus opacus RKJ300
Manually annotated by BRENDA team