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1.14.13.35: anthranilate 3-monooxygenase (deaminating)

This is an abbreviated version!
For detailed information about anthranilate 3-monooxygenase (deaminating), go to the full flat file.

Word Map on EC 1.14.13.35

Reaction

anthranilate
+
NADPH
+
H+
+
O2
=
2,3-Dihydroxybenzoate
+
NADP+
+
NH3

Synonyms

anthranilate 2,3-dioxygenase (deaminating), anthranilate 2,3-hydroxylase (deaminating), anthranilate hydroxylase, anthranilate hydroxylase (deaminating), anthranilic hydroxylase, EC 1.14.12.2

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.35 anthranilate 3-monooxygenase (deaminating)

Activating Compound

Activating Compound on EC 1.14.13.35 - anthranilate 3-monooxygenase (deaminating)

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-Aminonicotinate
-
activates
3-Hydroxyanthranilate
-
induces
anthranilate
-
induces, the enzyme activity increases with an increase in the concentration of anthranilate in the growth medium, optimal amounts of the enzyme are synthesized when the concentration of anthranilate is 1 mg/ml, further increase in the concentration results in a considerable decrease in the growth of the organism as well in the enzyme activity
indole
-
0.02% induces the enzyme 516fold
kynurenine
-
induces
L-tryptophan
N-Formyl anthranilate
-
activates
salicylate