1.14.13.39: nitric-oxide synthase (NADPH)

This is an abbreviated version!
For detailed information about nitric-oxide synthase (NADPH), go to the full flat file.

Word Map on EC 1.14.13.39

1.14.13.39

artery

necrosis

lipopolysaccharide

l-name

lps

tnf

cardiovascular

cox-2

nitrite

cyclooxygenase-2

vessel

hypertension

cardiac

lps-induced

dismutase

cerebral

vasodilation

nerve

aortic

ischemia

pulmonary

prostaglandin

myocardial

cgmp

ng-nitro-l-arginine

factor-alpha

coronary

acetylcholine

wistar

endothelium-dependent

tnf-alpha

peroxynitrite

contractile

neuroprotective

lps-stimulated

reperfusion

nf-kappab

nitrotyrosine

microglia

interferon-gamma

nitroprusside

ifn-gamma

vasoconstriction

guanylate

vasorelaxation

il-1beta

lipopolysaccharide-induced

erectile

endothelin-1

guanylyl

pharmacology

medicine

Reaction

2 L-arginine + 2 NADPH + 2 H+ + 2 O2 = 2 Nomega-hydroxy-L-arginine + 2 NADP⁺ + 2 H2O

Synonyms

bacterial nitric oxide synthase, bacterial nitric-oxide synthase, bNOS, bsNOS, cb-NOS, cytokine inducible NOS, DNOS, e-NOS, EC-NOS, endothelial nitric oxide synthase, endothelial nitric-oxide synthase, endothelial NO synthase, endothelial NOS, endothelium-derived relaxation factor-forming enzyme, endothelium-derived relaxing factor synthase, eNOS, i-NOS, inducible nitric oxide synthase, inducible nitric-oxide synthase, inducible NO synthase, inducible NOS, iNOS, mitochondrial NO synthase, mitochondrial-specific nitric oxide synthase, mtNOS, n-NOS, NADPH diaphorase, NADPH-d, NADPH-diaphorase, NADPHd, neuronal nitric oxide synthase, neuronal nitric-oxide synthase, neuronal NO synthase, neuronal NOS, nicotinamide adenine dinucleotide phosphate-diaphorase, nitric oxid synthase, nitric oxide synthase, nitric oxide synthase-like protein, nitric oxide synthetase, nitric-oxide synthase, nNOS, nNOSalpha, NO synthase, NO synthase type I, NO synthase type II, NO synthase type III, NO-synthase, NOS, NOS I, NOS-2, NOS1, NOS2, NOS3, synthetase, nitric oxide

Results	in table
52	Activating Compound
4387	AA Sequence
6	Application
1	CAS Registry Number
52	Cloned(Commentary)
373	Cofactor
6	Crystallization (Commentary)
40825	Disease/ Diagnostics
26	Expression
36	General Information
18	General Stability
23	IC50 Value
214	Inhibitors
51	Ki Value [mM]
99	KM Value [mM]
96	Localization
113	Metals/Ions
51	Molecular Weight [Da]
106	Natural Substrates/ Products (Substrates)
2027	Organism
5	Pathway
1313	PDB ID
49	pH Optimum
1	pH Range
4	pH Stability
10	Posttranslational Modification
43	Protein Variants
66	Purification (Commentary)
31	Reaction
3	Reaction Type
220	Reference
1	Renatured (Commentary)
434	Source Tissue
57	Specific Activity [micromol/min/mg]
14	Storage Stability
324	Substrates and Products (Substrate)
68	Subunits
320	Synonyms
1	Systematic Name
72	Temperature Optimum [°C]
3	Temperature Stability [°C]
25	Turnover Number [1/s]

1.14.13.39: nitric-oxide synthase (NADPH)

Reaction

Synonyms

ECTree

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Synonyms

Synonyms on EC 1.14.13.39 - nitric-oxide synthase (NADPH)