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1.14.13.50: pentachlorophenol monooxygenase

This is an abbreviated version!
For detailed information about pentachlorophenol monooxygenase, go to the full flat file.

Word Map on EC 1.14.13.50

Reaction

2,3,5,6-Tetrachlorophenol
+
NADPH
+
H+
+
O2
=
2,3,5,6-tetrachlorohydroquinone
+
NADP+
+
H2O

Synonyms

CpsB, dechlorinase, pentachlorophenol, GM610_18120, oxygenase, pentachlorophenol 4-mono-, PCB hydroxylase, PCP 4-monooxygenase, PCP hydroxylase, PCP-4-monooxygenase, PCP-monooxygenase, PCP4MO, PcpB, PcpD, pentachlorophenol 4-mono-oxygenase, pentachlorophenol 4-monooxygenase, pentachlorophenol dechlorinase, pentachlorophenol dehalogenase, pentachlorophenol hydroxylase, pentachlorophenol monooxygenase, pentachlorophenol-4-monooxygenase, Phe4MO, tetrachlorobenzoquinone reductase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.13.50 pentachlorophenol monooxygenase

Reference

Reference on EC 1.14.13.50 - pentachlorophenol monooxygenase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schenk, T.; Muller, R.; Mörsberger, F.; Otto, M.K.; Lingens, F.
Enzymatic dehalogenation of pentachlorophenol by extracts from Arthrobacter sp. strain ATCC 33790
J. Bacteriol.
171
5487-5491
1989
Arthrobacter sp.
Manually annotated by BRENDA team
Schenk, T.; Muller, R.; Lingens, F.
Mechanism of enzymatic dehalogenation of pentachlorophenol by Arthrobacter sp. strain ATCC 33790
J. Bacteriol.
172
7272-7274
1990
Arthrobacter sp.
Manually annotated by BRENDA team
Xun, L.; Orser, C.S.
Purification and properties of pentachlorophenol hydroxylase, a flavoprotein from Flavobacterium sp. strain ATCC 39723 [published erratum appears in J Bacteriol 1992 Aug;174(15):5176]
J. Bacteriol.
173
4447-4453
1991
Flavobacterium sp.
Manually annotated by BRENDA team
Xun, L.; Topp, E.; Orser, C.S.
Diverse substrate range of a Flavobacterium pentachlorophenol hydroxylase and reaction stoichiometries
J. Bacteriol.
174
2898-2902
1992
Flavobacterium sp.
Manually annotated by BRENDA team
Topp, E.; Xun, L.; Orser, C.S.
Biodegradation of the herbicide bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) by purified pentachlorophenol hydroxylase and whole cells of Flavobacterium sp. strain ATCC 39723 is accompanied by cyanogenesis
Appl. Environ. Microbiol.
58
502-506
1992
Flavobacterium sp.
Manually annotated by BRENDA team
Leung, K.T.; Campbell, S.; Gan, Y.; White, D.C.; Lee, H.; Trevors, J.T.
The role of the Sphingomonas species UG30 pentachlorophenol-4-monooxygenase in p-nitrophenol degradation
FEMS Microbiol. Lett.
173
247-253
1999
Flavobacterium sp., Sphingomonas sp. (O68977), Sphingomonas sp. UG30 (O68977)
Manually annotated by BRENDA team
Orser, C.S.; Lange, C.C.; Xun, L.; Zahrt, T.C.; Schneider, B.J.
Cloning, sequence analysis, and expression of the Flavobacterium pentachlorophenol-4-monooxygenase gene in Escherichia coli
J. Bacteriol.
175
411-416
1993
Flavobacterium sp. (P42535), Flavobacterium sp.
Manually annotated by BRENDA team
Lange, C.C.; Schneider, B.J.; Orser, C.S.
Verification of the role of PCP 4-monooxygenase in chlorine elimination from pentachlorophenol by Flavobacterium sp. strain ATCC 39723
Biochem. Biophys. Res. Commun.
219
146-149
1996
Flavobacterium sp.
Manually annotated by BRENDA team
Wang, H.; Tiirola, M.A.; Puhakka, J.A.; Kulomaa, M.S.
Production and characterization of the recombinant Sphingomonas chlorophenolica pentachlorophenol 4-monooxygenase
Biochem. Biophys. Res. Commun.
289
161-166
2001
Flavobacterium sp.
Manually annotated by BRENDA team
Wang, H.; Marjomaki, V.; Ovod, V.; Kulomaa, M.S.
Subcellular localization of pentachlorophenol 4-monooxygenase in Sphingobium chlorophenolicum ATCC 39723
Biochem. Biophys. Res. Commun.
299
703-709
2002
Flavobacterium sp.
Manually annotated by BRENDA team
Thakur, I.S.; Verma, P.; Upadhayaya, K.
Molecular cloning and characterization of pentachlorophenol-degrading monooxygenase genes of Pseudomonas sp. from the chemostat
Biochem. Biophys. Res. Commun.
290
770-774
2002
Pseudomonas sp., Pseudomonas sp. IST 103
Manually annotated by BRENDA team
Nakamura, T.; Motoyama, T.; Hirono, S.; Yamaguchi, I.
Identification, characterization, and site-directed mutagenesis of recombinant pentachlorophenol 4-monooxygenase
Biochim. Biophys. Acta
1700
151-159
2004
Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Nakamura, T.; Motoyama, T.; Hirokawa, T.; Hirono, S.; Yamaguchi, I.
Computer-aided modeling of pentachlorophenol 4-monooxygenase and site-directed mutagenesis of its active site
Chem. Pharm. Bull.
51
1293-1298
2003
Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Shah, S.; Thakur, I.S.
Enzymatic dehalogenation of pentachlorophenol by Pseudomonas fluorescens of the microbial community from tannery effluent
Curr. Microbiol.
47
65-70
2003
Pseudomonas fluorescens
Manually annotated by BRENDA team
Dai, M.; Rogers, J.B.; Warner, J.R.; Copley, S.D.
A previously unrecognized step in pentachlorophenol degradation in Sphingobium chlorophenolicum is catalyzed by tetrachlorobenzoquinone reductase (PcpD)
J. Bacteriol.
185
302-310
2003
Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Crawford, R.L.; Jung, C.M.; Strap, J.L.
The recent evolution of pentachlorophenol (PCP)-4-monooxygenase (PcpB) and associated pathways for bacterial degradation of PCP
Biodegradation
18
525-539
2006
Sphingomonas sp., Sphingobium chlorophenolicum, Mycolicibacterium chlorophenolicum
Manually annotated by BRENDA team
Su, Y.; Chen, L.; Bandy, B.; Yang, J.
The Catalytic Product of Pentachlorophenol 4-Monooxygenase is Tetra-chlorohydroquinone rather than Tetrachlorobenzoquinone
Open Microbiol. J.
2
100-106
2008
Sphingobium chlorophenolicum (P42535), Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Hlouchova, K.; Rudolph, J.; Pietari, J.M.; Behlen, L.S.; Copley, S.D.
Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum
Biochemistry
51
3848-3860
2012
Sphingobium chlorophenolicum
Manually annotated by BRENDA team
Rudolph, J.; Erbse, A.H.; Behlen, L.S.; Copley, S.D.
A radical intermediate in the conversion of pentachlorophenol to tetrachlorohydroquinone by Sphingobium chlorophenolicum
Biochemistry
53
6539-6549
2014
Sphingobium chlorophenolicum (P42535)
Manually annotated by BRENDA team
Joshi, V.; Prewitt, M.; Ma, D.; Borazjani, H.
Enhanced remediation of pentachlorophenol (PCP)-contaminated groundwater by bioaugmentation with known PCP-degrading bacteria
Bioremediat. J.
19
160-170
2015
Sphingobium chlorophenolicum (P42535), Sphingobium chlorophenolicum L-1 (P42535)
-
Manually annotated by BRENDA team
Aregbesola, O.A.; Kumar, A.; Mokoena, M.P.; Olaniran, A.O.
Classic pentachlorophenol hydroxylating phenylalanine 4-monooxygenase from indigenous Bacillus tropicus strain AOA-CPS1 cloning, overexpression, purification, characterization and structural homology modelling
Appl. Biochem. Biotechnol.
194
635-658
2022
Bacillus tropicus, Bacillus tropicus AOA-CPS1
Manually annotated by BRENDA team
Aregbesola, O.A.; Kumar, A.; Mokoena, M.P.; Olaniran, A.O.
Whole-genome sequencing, genome mining, metabolic reconstruction and evolution of pentachlorophenol and other xenobiotic degradation pathways in Bacillus tropicus strain AOA-CPS1
Funct. Integr. Genomics
21
171-193
2021
Bacillus tropicus, Bacillus tropicus AOA-CPS1
Manually annotated by BRENDA team