1.14.13.83: precorrin-3B synthase

This is an abbreviated version!
For detailed information about precorrin-3B synthase, go to the full flat file.

Reaction

Synonyms

Bmei0715, CobG, CobZ, precorrin-3A monooxygenase, precorrin-3X synthase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

1.14.13.83 precorrin-3B synthase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
1662	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
3	Cofactor
3	General Information
1	General Stability
6	Metals/Ions
7	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
11	Organism
5	Pathway
19	Protein Variants
5	Purification (Commentary)
2	Reaction
11	Reference
1	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
17	Synonyms
1	Systematic Name

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 1.14.13.83 - precorrin-3B synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Systematic Name Search

precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)

An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively.