1.14.14.29: 25/26-hydroxycholesterol 7alpha-hydroxylase
This is an abbreviated version!
For detailed information about 25/26-hydroxycholesterol 7alpha-hydroxylase, go to the full flat file.
Word Map on EC 1.14.14.29
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1.14.14.29
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oxysterols
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bile
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cyp27a1
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27-hydroxycholesterol
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paraplegia
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dehydroepiandrosterone
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neurosteroids
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7alpha-hydroxylation
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27-hydroxylase
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interferon-stimulated
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lithogenic
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cholesterol-25-hydroxylase
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7alpha-hydroxy-dhea
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5alpha-androstane-3beta,17beta-diol
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7-hydroxylation
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cyp2b9
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medicine
- 1.14.14.29
- oxysterols
- bile
- cyp27a1
- 27-hydroxycholesterol
- paraplegia
- dehydroepiandrosterone
-
neurosteroids
-
7alpha-hydroxylation
-
27-hydroxylase
-
interferon-stimulated
-
lithogenic
- cholesterol-25-hydroxylase
-
7alpha-hydroxy-dhea
- 5alpha-androstane-3beta,17beta-diol
-
7-hydroxylation
-
cyp2b9
- medicine
Reaction
Synonyms
25-hydroxycholesterol 7alpha-hydroxylase, 25-hydroxycholesterol 7alpha-monooxygenase, 25-hydroxycholesterol-7alpha-hydroxylase, cholesterol 25-hydroxylase, Cyp39a1, CYP7B, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, CYPB1, cytochome P450 7B1, cytochrome P-450 oxysterol 7-alpha-hydroxylase, EC 1.14.13.100, EC 1.14.13.60, oxysterol 7 alpha-hydroxylase, oxysterol 7alpha-hydroxylase, oxysterol-7alpha-hydroxylase, Steroid hydroxylase
ECTree
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Activating Compound
Activating Compound on EC 1.14.14.29 - 25/26-hydroxycholesterol 7alpha-hydroxylase
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estrogen
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overexpression of PI3K or Akt significantly increases estrogenic upregulation of CYP7B1 in Hep-G2 cells. Estrogen receptor interacts with the PI3K/Akt pathway without binding to the CYP7B1 gene. In HEK293 cells, CYP7B1 transcription is much less affected by Akt, indicating that the mechanism for upregulation of CYP7B1 is different in different cell types