Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.15.18: calcidiol 1-monooxygenase

This is an abbreviated version!
For detailed information about calcidiol 1-monooxygenase, go to the full flat file.

Word Map on EC 1.14.15.18

Reaction

calcidiol
+ 2 reduced adrenodoxin + 2 H+ +
O2
=
calcitriol
+ 2 oxidized adrenodoxin +
H2O

Synonyms

1-hydroxylase-25-hydroxyvitamin D3, 1-OHase, 1alpha,25-dihydroxyvitamin D hydroxylase, 1alpha-hydroxylase, 1alpha-OHase, 1alphaOHase, 25 hydroxy-vitamin D3-1alpha hydroxylase, 25(OH)VD3 1alpha-hydroxylase, 25-hydroxy D3-1alpha-hydroxylase, 25-hydroxycholecalciferol 1-hydroxylase, 25-hydroxycholecalciferol 1-monooxygenase, 25-hydroxycholecalciferol 1alpha-hydroxylase, 25-hydroxycholecalciferol-1-hydroxylase, 25-hydroxyvitamin D 1alpha-hydroxylase, 25-hydroxyvitamin D-1 alpha-hydroxylase, 25-hydroxyvitamin D-1-alpha-hydroxylase, 25-hydroxyvitamin D-1alpha-hydroxylase, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25-hydroxyvitamin D3-1alpha-hydroxylase, 25-hydroxyvitamin-D3-1alpha-hydroxylase, CYB27B1, CYP1alpha, CYP27A, CYP27B1, cytochrome P450 25-hydroxyvitamin D3-1alpha-hydroxylase, EC 1.14.13.13, extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase, extra-renal 25-hydroxyvitamin D3 1alpha-hydroxylase, hydroxylase, 25-hydroxcholecalciferol 1-, More, oxygenase, 25-hydroxycholecalciferol 1-mono-, P450 cytochrome 25-hydroxyvitamin D3 1alpha-hydroxylase, VD3 25-hydroxylase, VDH, vitamin D 1alpha-hydroxylase, vitamin D hydroxylase, vitamin D3 25- and 1alpha-hydroxylase, vitamin D3 25-hydroxylase, vitamin D3 hydroxylase, [25(OH)D3]-1alpha-hydroxylase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.18 calcidiol 1-monooxygenase

Natural Substrates Products

Natural Substrates Products on EC 1.14.15.18 - calcidiol 1-monooxygenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(24R),25-dihydroxycholecalciferol + NADPH + O2
1alpha,24,25-trihydroxycholecalciferol + NADP+ + H2O
show the reaction diagram
25-hydroxycholecalciferol + NADPH + O2
calcitriol + NADP+ + H2O
show the reaction diagram
25-hydroxyvitamin D + NADPH + O2
1alpha,25-dihydroxyvitamin D + NADP+ + H2O
show the reaction diagram
25-hydroxyvitamin D2 + NADPH + H+ + O2
1,25-dihydroxyvitamin D2 + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
25-hydroxyvitamin D3 + H+ + O2
25-hydroxyvitamin D3 + H2O
show the reaction diagram
-
-
-
?
25-hydroxyvitamin D3 + NADPH + H+ + O2
1,25-dihydroxyvitamin D3 + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
25-hydroxyvitamin D3 + NADPH + O2
1alpha,25-dihydroxyvitamin D3 + NADP+ + H2O
show the reaction diagram
cholecalciferol + NADPH + O2
25-hydroxyvitamin D3 + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
additional information
?
-