1.14.15.4: steroid 11beta-monooxygenase
This is an abbreviated version!
For detailed information about steroid 11beta-monooxygenase, go to the full flat file.
Word Map on EC 1.14.15.4
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1.14.15.4
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hypertension
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cortisol
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adrenocortical
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steroidogenic
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corticosterone
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angiotensin
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hyperplasia
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acth
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zona
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glucocorticoid
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steroidogenesis
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mineralocorticoid
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glomerulosa
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adenoma
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21-hydroxylase
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renin
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11-deoxycortisol
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deoxycorticosterone
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fasciculata
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metyrapone
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11-deoxycorticosterone
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beta-hydroxysteroid
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pregnenolone
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angiotensinogen
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cushing
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cyp11a1
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virilization
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androstenedione
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cyp21
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spironolactone
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18-hydroxycorticosterone
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p450scc
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adrenodoxin
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17-hydroxyprogesterone
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hirsutism
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beta-hydroxylation
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atp1a1
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acth-stimulated
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17alpha-hydroxylase
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cortisol-producing
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etomidate
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hsd3b2
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hypokalemia
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medicine
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trilostane
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apccs
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salt-wasting
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11-ketotestosterone
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low-renin
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drug development
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liddle
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extra-adrenal
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analysis
- 1.14.15.4
- hypertension
- cortisol
-
adrenocortical
-
steroidogenic
- corticosterone
- angiotensin
- hyperplasia
- acth
- zona
- glucocorticoid
-
steroidogenesis
-
mineralocorticoid
- glomerulosa
- adenoma
- 21-hydroxylase
- renin
- 11-deoxycortisol
- deoxycorticosterone
- fasciculata
- metyrapone
- 11-deoxycorticosterone
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beta-hydroxysteroid
- pregnenolone
- angiotensinogen
- cushing
- cyp11a1
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virilization
- androstenedione
- cyp21
- spironolactone
- 18-hydroxycorticosterone
- p450scc
- adrenodoxin
- 17-hydroxyprogesterone
- hirsutism
-
beta-hydroxylation
- atp1a1
-
acth-stimulated
- 17alpha-hydroxylase
-
cortisol-producing
- etomidate
- hsd3b2
- hypokalemia
- medicine
- trilostane
-
apccs
-
salt-wasting
- 11-ketotestosterone
-
low-renin
- drug development
-
liddle
-
extra-adrenal
- analysis
Reaction
Synonyms
11-hydroxylase, 11 beta-hydroxylase, 11-beta hydroxylase, 11-beta-hydroxylase, 11-hydroxylase, 11beta hydroxylase, 11beta-hydroxylase, ALDOS, Aldosterone synthase, Aldosterone-synthesizing enzyme, C450XIB2, CYP11B1, CYP11B2, cyp11beta, CYPXIB, CYPXIB1, CYPXIB2, CYPXIB3, cytochrome 11beta-hydroxylase, cytochrome P-45011-beta, cytochrome P450 11B1, cytochrome P450 11B2, cytochrome P450 11beta-hydroxylase, cytochrome P45011beta, cytochrome P45011beta-hydroxylase, EC 1.14.1.6, EC 1.99.1.7, P-450(11 beta,aldo), P-450Aldo, P-450c11, P-450C18, P-450XIB1, P450 11beta-hydroxylase, P450(11 beta)-DS, P45011beta, P450C11, Steroid 11-beta-hydroxylase, steroid 11-hydroxylase, steroid 11beta-hydroxylase, steroid 11beta-monooxygenase, steroid 11beta/18-hydroxylase, Steroid 18-hydroxylase, steroid-11beta-hydroxylase
ECTree
1.14.15.4 steroid 11beta-monooxygenaseAdvanced search results
results (
results (Source Tissue
Source Tissue on EC 1.14.15.4 - steroid 11beta-monooxygenase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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isolated mitochondria from human NCI-H295 adrenal cells
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corresponding to mammalian adrenal gland, P-450(11beta,aldo) and adrenodoxin reductase exist more in outer regions of frogs during the spring and the summer
additional information
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285387, 285389, 285390, 285391, 285393, 285394, 285395, 285396, 285398, 285399, 285400, 285402, 285403, 285404, 285405
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capsular portion in zona glomerulosa cells, decapsular in zonae fasciculata and reticularis
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enzyme expression during sex differentiation and in adult fish at the breeding stage, the enzyme level is higher in the male phase than during testicular differentiation or in the female phase
during development all zebrafish males first develop a juvenile ovary, that later degenerates and transforms into a testis, the enzyme is involved, but not inducing, in gonadal transformation in the zebrafish, but its localization is not related to the position of degenerating oocytes, overview
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CYP11B shows a highly dimorphic expression pattern throughout gonadogenesis
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cardiac tissue from several rat models of cardiovascular pathology, low constitutive expression, which seems to be of no physiologic relevance
fully expressed, markedly up-regulated at the onset of testicular development
additional information
the mRNA of cyp11b is detected in all the adult organs tested
additional information
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the mRNA of cyp11b is detected in all the adult organs tested
additional information
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gene expression during the thermosensitive period and gonadogenesis, maximally residual activity in tissues other than head kidney and gonads, overview
additional information
genes differentially expressed during the sex change process. The ratio of male to female expression (male P45011beta/female P45011beta) is higher than 20
additional information
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genes differentially expressed during the sex change process. The ratio of male to female expression (male P45011beta/female P45011beta) is higher than 20
additional information
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no signal: brain, pituitary, gill, heart, liver, pyloric caeca, intestine, ovary, muscle, skin, blood
