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1.14.15.7: choline monooxygenase

This is an abbreviated version!
For detailed information about choline monooxygenase, go to the full flat file.

Word Map on EC 1.14.15.7

Reaction

choline
+
O2
+
reduced ferredoxin
+ 2 H+ =
betaine aldehyde hydrate
+
H2O
+
oxidized ferredoxin

Synonyms

AhCMO, AnCMO, ApCMO, choline monooxygenase, choline oxygenase, CMO, CMO1, EC 1.14.14.4, Os06g48510

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.15.7 choline monooxygenase

Engineering

Engineering on EC 1.14.15.7 - choline monooxygenase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C181A
second Cys in the putative consensus sequence for coordination of Rieske-type cluster to Ser, Ala and Thr, essential for activity
C181S
second Cys in the putative consensus sequence for coordination of Rieske-type cluster to Ser, Ala and Thr, essential for activity
C181T
second Cys in the putative consensus sequence for coordination of Rieske-type cluster to Ser, Ala and Thr, essential for activity
H287A
first His in the putative consensus sequence for coordination of mononuclear non-heme Fe to Gly, Ala, and Val, His-287 is essential for activity
H287G
first His in the putative consensus sequence for coordination of mononuclear non-heme Fe to Gly, Ala, and Val, His-287 is essential for activity
H287V
first His in the putative consensus sequence for coordination of mononuclear non-heme Fe to Gly, Ala, and Val, His-287 is essential for activity
additional information