1.14.15.8: steroid 15beta-monooxygenase
This is an abbreviated version!
For detailed information about steroid 15beta-monooxygenase, go to the full flat file.
Word Map on EC 1.14.15.8
-
1.14.15.8
-
megaterium
-
p-450-dependent
-
ferredoxins
-
synthesis
-
adrenodoxin
-
autologous
-
triterpene
-
11-oxidase
-
testosterone
-
flavodoxin
-
flavoprotein
-
hydroxylases
-
aniline
-
11-deoxycortisol
-
nadph-dependent
-
fmn-containing
-
paramagnetic
-
iron-sulfur
-
biocatalyst
-
11-keto
-
11-deoxycorticosterone
- 1.14.15.8
- megaterium
-
p-450-dependent
- ferredoxins
- synthesis
- adrenodoxin
-
autologous
-
triterpene
-
11-oxidase
- testosterone
- flavodoxin
- flavoprotein
- hydroxylases
- aniline
- 11-deoxycortisol
-
nadph-dependent
-
fmn-containing
-
paramagnetic
-
iron-sulfur
-
biocatalyst
-
11-keto
- 11-deoxycorticosterone
Reaction
Synonyms
15beta-hydroxylase, 15beta-hydroxylase CYP106A2, BmCYP106A2, Cyp106A1, CYP106A2, cytochrome P-450meg, cytochrome P450meg, steroid-15-beta-monooxygenase
ECTree
Advanced search results
Activating Compound
Activating Compound on EC 1.14.15.8 - steroid 15beta-monooxygenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
heme
-
the heme content of cytochrome P-450meg is 0.94 nmol of heme per nmol of cytochrome P-450
Iron
-
it is possible to resolve the hydroxylase system into three proteins: a strictly NADPH-dependent FMN-containing flavoprotein (megaredoxin reductase), an iron-sulfur protein (megaredoxin), and cytochrome P-450 (P-450meg). The activity of the 15beta-hydroxylase system is fully reconstituted upon combination of these three proteins and addition of NADPH. Megaredoxin has an apparent sulfur to iron ratio of 0.98 and shows g-signals at 1.90, 1.93, and 2.06 when analyzed by electron paramagnetic resonance spectroscopy