1.14.16.5: alkylglycerol monooxygenase

This is an abbreviated version!
For detailed information about alkylglycerol monooxygenase, go to the full flat file.

Reaction

Synonyms

AGMO, alkylglycerol mono-oxygenase, alkylglycerol monooxygenase, EC 1.14.99.17, glyceryl ether hydroxylase, glyceryl ether monooxygenase, glyceryl ether oxidase, glyceryl ether oxygenase, glyceryl ether-cleaving enzyme, glyceryl etherase, glyceryl-ether cleaving enzyme, O-alkylglycerol monooxygenase, oxygenase, glyceryl ether mono-, PRUB680

ECTree

     1 Oxidoreductases

         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

             1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor

                1.14.16.5 alkylglycerol monooxygenase

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Results	in table
6	Activating Compound
39	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
30	Cofactor
5	Disease/ Diagnostics
1	Expression
2	General Information
3	IC50 Value
61	Inhibitors
15	Ki Value [mM]
48	KM Value [mM]
24	Localization
5	Metals/Ions
8	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
41	Organism
5	pH Optimum
1	pH Range
24	Protein Variants
5	Purification (Commentary)
3	Reaction
4	Reaction Type
41	Reference
47	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
130	Substrates and Products (Substrate)
6	Subunits
24	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 1.14.16.5 - alkylglycerol monooxygenase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-hydroxyalkyl-sn-glycerol + dihydrobiopterin + H2O

2 entries

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-O-alkyl-sn-glycerol + dihydrobiopterin + H2O

3 entries

1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine + tetrahydrobiopterin + O2

glycerophosphocholine + alkylaldehyde + dihydrobiopterin + H2O

Mus musculus

-

1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine is lyso-platelet activating factor

726881

-

-

?

1-O-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-O-(1-hydroxyalkyl)-sn-glycerol + dihydrobiopterin + H2O

Mus musculus

-

-

726881

-

-

?

1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2

1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O

2 entries

lyso-alkyl-glycerol phospholipid + tetrahydrobiopterin + O2

1-O-(1-hydroxyalkyl)-sn-glycerol + 6,7-[8]-dihydrobiopterin + H2O

Rattus norvegicus

-

-

727650

-

-

?

lyso-platelet activating factor + tetrahydrobiopterin + O2

?

3 entries

prodigiosin + tetrahydrobiopterin + O2

cycloprodigiosin + dihydrobiopterin + H2O

Pseudoalteromonas rubra

-

-

745840

-

-

?

additional information

?

-

Rattus norvegicus

-

catalyses the cleavage of lipid ethers into glycerol and the corresponding aldehyde

696542

-

-

?

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-hydroxyalkyl-sn-glycerol + dihydrobiopterin + H2O

Rattus norvegicus

-

-

688220

-

-

?

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-hydroxyalkyl-sn-glycerol + dihydrobiopterin + H2O

Rattus norvegicus

-

enzyme plays an essential role in conjugation with the cleavage enzyme in the regulation of cellular levels of -alkyl moieties in glycerolipids

438645

-

-

?

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-O-alkyl-sn-glycerol + dihydrobiopterin + H2O

Homo sapiens

-

-

745497

-

-

?

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-O-alkyl-sn-glycerol + dihydrobiopterin + H2O

Homo sapiens

Q6ZNB7

-

745589

-

-

?

1-alkyl-sn-glycerol + tetrahydrobiopterin + O2

1-O-alkyl-sn-glycerol + dihydrobiopterin + H2O

Mus musculus

-

-

746303

-

-

?

1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2

1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O

Caenorhabditis elegans

-

-

727650

-

-

?

1-O-alkyl-sn-glycerol 3-phosphate + tetrahydrobiopterin + O2

1-O-(1-hydroxyalkyl)-sn-glycerol 3-phosphate + 6,7-[8]-dihydrobiopterin + H2O

Danio rerio

-

-

727650

-

-

?

lyso-platelet activating factor + tetrahydrobiopterin + O2

?

Caenorhabditis elegans

-

good substrate

727650

-

-

?

lyso-platelet activating factor + tetrahydrobiopterin + O2

?

Danio rerio

-

good substrate

727650

-

-

?

lyso-platelet activating factor + tetrahydrobiopterin + O2

?

Rattus norvegicus

-

good substrate

727650

-

-

?