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1.14.19.10: icosanoyl-CoA 5-desaturase

This is an abbreviated version!
For detailed information about icosanoyl-CoA 5-desaturase, go to the full flat file.

Word Map on EC 1.14.19.10

Reaction

icosanoyl-CoA
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
(Z)-icos-5-enoyl-CoA
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

acyl-CoA DELTA5 desaturase, Delta-5 acyl-CoA desaturase, DELTA5 desaturase, DELTA5DS

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.10 icosanoyl-CoA 5-desaturase

Systematic Name

Systematic Name on EC 1.14.19.10 - icosanoyl-CoA 5-desaturase

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SYSTEMATIC NAME
IUBMB Comments
icosanoyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6 cis-dehydrogenating)
The enzyme, characterized from the plant Limnanthes douglasii (meadowfoam), is involved in the biosynthesis of (5Z)-icos-5-enoate, an unusual monounsaturated fatty acid that makes up to 60% of the total fatty acids in Limnanthes sp. seed oil. The enzyme only acts on saturated fatty acids.