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1.14.19.21: cholesterol 7-desaturase

This is an abbreviated version!
For detailed information about cholesterol 7-desaturase, go to the full flat file.

Word Map on EC 1.14.19.21

Reaction

cholesterol
+
O2
+
NAD(P)H
+
H+
=
cholesta-5,7-dien-3beta-ol
+
NAD(P)+
+ 2 H2O

Synonyms

C-7 cholesterol desaturase, C7-Des, cholesterol 7,8-dehydrogenase, DAF-36, DAF-36/Neverland, Des7, Des7p, Neverland, Nvd, PmNvd, Rieske domain oxygenase Neverland, sterol C7(8)-desaturase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.21 cholesterol 7-desaturase

Cloned

Cloned on EC 1.14.19.21 - cholesterol 7-desaturase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amiino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, quantitative RT-PCR expression analysis
expressed in Drosophila melanogaster S2 cells
expressed in Sf9 cells
-
expressed in Sf9 insect cells