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BRENDA support

1.14.19.26: acyl-[acyl-carrier-protein] 6-desaturase

This is an abbreviated version!
For detailed information about acyl-[acyl-carrier-protein] 6-desaturase, go to the full flat file.

Reaction

palmitoyl-[acyl-carrier protein]
+ 2 reduced ferredoxin [iron-sulfur] cluster +
O2
+ 2 H+ =
(6Z)-hexadec-6-enoyl-[acyl-carrier protein]
+ 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O

Synonyms

DELTA6 16:0-ACP desaturase, DELTA6 desaturase, DELTA6 palmitoyl-ACP desaturase, DELTA6-16:0-ACP desaturase, DELTA6-palmitoyl (16:0)-ACP desaturase, DELTA6-sphingolipid desaturase, DES6

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.26 acyl-[acyl-carrier-protein] 6-desaturase

Reference

Reference on EC 1.14.19.26 - acyl-[acyl-carrier-protein] 6-desaturase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Cahoon, E.B.; Lindqvist, Y.; Schneider, G.; Shanklin, J.
Redesign of soluble fatty acid desaturases from plants from altered substrate specificity and double bond position
Proc. Natl. Acad. Sci. USA
94
4872-4877
1997
Thunbergia alata (Q41510)
Manually annotated by BRENDA team
Cahoon, E.B.; Cranmer, A.M.; Shanklin, J.; Ohlrogge, J.B.
DELTA6 Hexadecenoic acid is synthesized by the activity of a soluble DELTA6 palmitoyl-acyl carrier protein desaturase in Thunbergia alata endosperm
J. Biol. Chem.
269
27519-27526
1994
Thunbergia alata (Q41510)
Manually annotated by BRENDA team
Marra, C.; de Alaniz, M.; Brenner, R.
Modulation of DELTA6 and DELTA5 rat liver microsomal desaturase activities by dexamethasone-induced factor
Biochim. Biophys. Acta
879
388-393
1986
Rattus norvegicus
Manually annotated by BRENDA team
Sperling, P.; Lee, M.; Girke, T.; Zaehringer, U.; Stymne, S.; Heinz, E.
A bifunctional delta-fatty acyl acetylenase/desaturase from the moss Ceratodon purpureus. A new member of the cytochrome b5 superfamily
Eur. J. Biochem.
267
3801-3811
2000
Ceratodon purpureus (A7UFH0)
Manually annotated by BRENDA team