1.14.19.29: sphingolipid 8-(E/Z)-desaturase

This is an abbreviated version, for detailed information about sphingolipid 8-(E/Z)-desaturase, go to the full flat file.

Reaction

a (4R)-4-hydroxysphinganine ceramide
+ 2 ferrocytochrome b5 +
O2
+ 2 H+ =
a (4R,8E)-4-hydroxysphing-8-enine ceramide
+ 2 ferricytochrome b5 + 2 H2O

Synonyms

8 fatty acid desaturase, 8-sphingolipid desaturase, D8A, D8D, DELTA8 Des, Delta8 sphingolipid desaturase, DELTA8(E,Z)-sphingolipid desaturase, DELTA8-sphingolipid desaturase, DELTA8-sphingolipid-desaturase, DES8, DXDES, LCB DELTA8 desaturase, SLD, SLD1, SLD2, sphingoid long-chain base DELTA8 desaturase, sphingolipid DELTA8-desaturase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
                1.14.19.29 sphingolipid 8-(E/Z)-desaturase