1.14.19.41: sterol 22-desaturase

This is an abbreviated version!
For detailed information about sterol 22-desaturase, go to the full flat file.

Word Map on EC 1.14.19.41

1.14.19.41

ergosterol

stigmasterol

azole

desaturases

ketoconazole

phytosterols

campesterol

beta-sitosterol

withanolides

withania

somnifera

xanthophyllomyces

dendrorhous

brassicasterol

14alpha-demethylase

sitosterol

Reaction

+ 2 H2O

Synonyms

C-22 sterol desaturase, CTP61, CYP61, CYP710A, CYP710A1, CYP710A11, CYP710A13, CYP710A14, CYP710A2, CYP710A4, cytochrome P-450 sterol DELTA22-desaturase, cytochrome P-45061, cytochrome P45061, DELTA22-desaturase, ERG5, Erg5p, P450 61, Sd1, sterol 22-desaturase, sterol C-22 desaturase, sterol C22 desaturase, sterol C22-desaturase, sterol DELTA22-desaturase

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.19 With oxidation of a pair of donors resulting in the reduction of O₂ to two molecules of water

1.14.19.41 sterol 22-desaturase

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Results	in table
16	AA Sequence
3	Cloned(Commentary)
15	Cofactor
1	Expression
6	General Information
6	IC50 Value
24	Inhibitors
2	kcat/KM [mM/s]
1	Ki Value [mM]
8	KM Value [mM]
10	Localization
8	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
31	Organism
5	Pathway
1	Protein Variants
3	Purification (Commentary)
1	Reaction
27	Reference
2	Source Tissue
29	Substrates and Products (Substrate)
11	Subunits
50	Synonyms
1	Systematic Name
5	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 1.14.19.41 - sterol 22-desaturase

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0.015

(20S)-21-isocyano-20-methylpregn-5-en-3beta-ol

Saccharomyces cerevisiae

at 27°C, pH not specified in the publication

733242

0.0000001 - 0.0000005

fluconazole

2 entries

0.0000001

itraconazole

[Candida] glabrata

calculated value, pH and temperature not specified in the publication

733104

0.0000001 - 0.0000002

ketoconazole

2 entries