1.14.19.41: sterol 22-desaturase
This is an abbreviated version!
For detailed information about sterol 22-desaturase, go to the full flat file.
Word Map on EC 1.14.19.41
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1.14.19.41
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ergosterol
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stigmasterol
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azole
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desaturases
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ketoconazole
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phytosterols
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campesterol
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beta-sitosterol
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withanolides
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withania
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somnifera
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xanthophyllomyces
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dendrorhous
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brassicasterol
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14alpha-demethylase
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sitosterol
- 1.14.19.41
- ergosterol
- stigmasterol
- azole
-
desaturases
- ketoconazole
- phytosterols
- campesterol
- beta-sitosterol
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withanolides
-
withania
- somnifera
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xanthophyllomyces
- dendrorhous
- brassicasterol
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14alpha-demethylase
- sitosterol
Reaction
Synonyms
C-22 sterol desaturase, CTP61, CYP61, CYP710A, CYP710A1, CYP710A11, CYP710A13, CYP710A14, CYP710A2, CYP710A4, cytochrome P-450 sterol DELTA22-desaturase, cytochrome P-45061, cytochrome P45061, DELTA22-desaturase, ERG5, Erg5p, P450 61, Sd1, sterol 22-desaturase, sterol C-22 desaturase, sterol C22 desaturase, sterol C22-desaturase, sterol DELTA22-desaturase
ECTree
1.14.19.41 sterol 22-desaturaseAdvanced search results
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results (Inhibitors
Inhibitors on EC 1.14.19.41 - sterol 22-desaturase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
(20S)-21-isocyano-20-methylpregn-5-en-3beta-ol
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complete inhibition at 0.15 mM
additional information
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not inhibited by desmosterol, 24-methylenecholesterol, and 24-bromocholesterol
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(3S,20S)-20-N-butylcarbamoylpregn-7-en-3beta-ol
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selective inhibitors of fungal sterol C22-desaturase. The inhibitor is subjected to antifungal susceptibility testing on patient isolates according to modified EUCAST guidelines. But, the organism shows no significant reduction of cell growth and/or viability up to an inhibitor concentration of 0.1 mg/ml. Thus the sterol C22-desaturase is not an attractive target for the development of antifungals
(3S,20S)-20-N-butylcarbamoylpregn-7-en-3beta-ol
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selective inhibitors of fungal sterol C22-desaturase. The inhibitor is subjected to antifungal susceptibility testing on patient isolates according to modified EUCAST guidelines. But, the organism shows no significant reduction of cell growth and/or viability up to an inhibitor concentration of 0.1 mg/ml. Thus the sterol C22-desaturase is not an attractive target for the development of antifungals
(3S,20S)-20-N-butylcarbamoylpregn-7-en-3beta-ol
selective inhibitors of fungal sterol C22-desaturase. The inhibitor is subjected to antifungal susceptibility testing on patient isolates according to modified EUCAST guidelines. But, the organism shows no significant reduction of cell growth and/or viability up to an inhibitor concentration of 0.1 mg/ml. Thus the sterol C22-desaturase is not an attractive target for the development of antifungals
