1.14.20.3: (5R)-carbapenem-3-carboxylate synthase

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Word Map on EC 1.14.20.3

1.14.20.3

epimerization

desaturation

oxygenase

carbapenams

bicyclic

biosynthesized

donate

Reaction

Synonyms

carbapenem synthase, CarC

ECTree

1 Oxidoreductases

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated

1.14.20.3 (5R)-carbapenem-3-carboxylate synthase

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1	Activating Compound
14	AA Sequence
3	Cloned(Commentary)
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1	General Information
3	Metals/Ions
1	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
9	Organism
6	Pathway
3	PDB ID
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9	Synonyms
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1	Temperature Optimum [°C]

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Activating Compound on EC 1.14.20.3 - (5R)-carbapenem-3-carboxylate synthase

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ascorbate

Pectobacterium carotovorum

activity with the natural substrate (3S,5S)-carbapenam-3-carboxylate in absence of ascorbate is 2% compared to the activity in presence of ascorbate. Ascorbate does not stimulate turnover of the (3S,5R)- or (3R,5R)-stereoisomers

722055