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1.14.99.22: ecdysone 20-monooxygenase

This is an abbreviated version!
For detailed information about ecdysone 20-monooxygenase, go to the full flat file.

Word Map on EC 1.14.99.22

Reaction

ecdysone
+
reduced acceptor
 +
O2
=
20-hydroxyecdysone
 +
acceptor
 +
H2O

Synonyms

alpha-ecdysone C-20 hydroxylase, BmE20OHase, Cyp314A1, E-20-M, E20-M, E20M, E20MO, E20OHase, ecdysone 20-hydroxylase, ecdysone 20-monooxygenase, shade, shd

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.99 Miscellaneous
                1.14.99.22 ecdysone 20-monooxygenase

Activating Compound

Activating Compound on EC 1.14.99.22 - ecdysone 20-monooxygenase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
20-hydroxyecdysone
-
injection of 20-hydroxyecdysone stimulates ecdysone 20-hydroxylase activity in the midgut
9-methoxy-1,4-anthraquinone
-
about 125% activity at 0.001 mM
ATP
-
increase of activity
dibutyryl-cGMP
-
activates E20M activity by 50fold, diminished by injections of guanylate cyclase inhibitors alone or combined with ecdysone agonist RH-5849
Juvenile hormone
-
-
L-dihydroxyphenylalanine
-
-
octopamine
additional information
-