1.15.1.1: superoxide dismutase
This is an abbreviated version!
For detailed information about superoxide dismutase, go to the full flat file.
Word Map on EC 1.15.1.1
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1.15.1.1
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catalase
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malondialdehyde
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gsh
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necrosis
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endothelial
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tnf
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wistar
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artery
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ascorbate
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gsh-px
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caspase-3
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cholesterol
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cardiac
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reperfusion
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neuroprotective
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sclerosis
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tbars
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anti-oxidant
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ischemia
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thiobarbituric
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myocardial
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triglyceride
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alt
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amyotrophic
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mime
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sacrificed
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chlorophyll
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neurotoxicity
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hippocampus
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myeloperoxidase
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infarct
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cerebral
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xanthine
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hepatotoxicity
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streptozotocin
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albino
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sham
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creatinine
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ischemia-reperfusion
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bcl-2
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s-transferase
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glutathione-s-transferase
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hepatoprotective
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diagnostics
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chemiluminescence
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synthesis
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gavage
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cardioprotective
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ceruloplasmin
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drug development
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oxygenase-1
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endothelium-dependent
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peroxynitrite
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environmental protection
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analysis
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biotechnology
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medicine
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agriculture
- 1.15.1.1
- catalase
- malondialdehyde
- gsh
- necrosis
- endothelial
- tnf
- wistar
- artery
- ascorbate
- gsh-px
- caspase-3
- cholesterol
- cardiac
-
reperfusion
-
neuroprotective
- sclerosis
-
tbars
-
anti-oxidant
- ischemia
-
thiobarbituric
- myocardial
- triglyceride
-
alt
-
amyotrophic
-
mime
-
sacrificed
- chlorophyll
-
neurotoxicity
- hippocampus
- myeloperoxidase
- infarct
- cerebral
- xanthine
-
hepatotoxicity
- streptozotocin
-
albino
-
sham
- creatinine
-
ischemia-reperfusion
- bcl-2
- s-transferase
- glutathione-s-transferase
-
hepatoprotective
- diagnostics
-
chemiluminescence
- synthesis
-
gavage
-
cardioprotective
- ceruloplasmin
- drug development
- oxygenase-1
-
endothelium-dependent
- peroxynitrite
- environmental protection
- analysis
- biotechnology
- medicine
- agriculture
Reaction
2 superoxide
+
2 H+
=
Synonyms
AhSOD, alr2938, AmSOD, APE0743, ApMn-SOD1, ApMn-SOD2, ASAC_0498, Ca-Cu,Zn SOD, cambialistic superoxide dismutase, Cg-EcSOD, chloroplastic Fe-SOD, Cj-Cu, Zn SOD, cMn-SOD, cMnSOD, cold-active superoxide dismutase, copper, zinc superoxide dismutase, copper-zinc superoxide dismutase, copper/zinc superoxide dismutase, copper/zinc-superoxide dismutase, CpSOD, CSD1, CSD2, CtSOD, Cu, Zn SOD, Cu, Zn superoxide dismutase, Cu, Zn-superoxide dismutase, Cu, ZnSOD, Cu,Zn superoxide dismutase, Cu,Zn-SOD, Cu,Zn-superoxide dismutase, Cu,ZnSOD, Cu-Zn SOD, Cu-Zn superoxide dismutase, Cu-Zn-SOD, Cu/Zn SOD, Cu/Zn superoxide dismutase, Cu/Zn superoxide dismutase 1, Cu/Zn-SOD, Cu/Zn-SODI, Cu/Zn-SODII, Cu/Zn-superoxide dismutase, Cu/ZnSOD, cuprein, CuZn superoxide dismutase, CuZn superoxide dismutase 1, CuZn-SOD, CuZn-superoxide dismutase, CuZnSOD, cytMnSOD, cytocuprein, cytoplasmic manganese SOD, cytosolic Cu/Zn superoxide dismutase, cytosolic Cu/Zn-SOD, cytosolic manganese superoxide dismutase, DaSOD, dhsod-1, dismutase, superoxide, EC-SOD, ecCuZnSOD, ECSOD, ElFe-SOD, ElSOD, erythrocuprein, erythrocyte superoxide dismutase, eSOD, extracellular copper-zinc superoxide dismutase, extracellular CuZnSOD, extracellular SOD, extracellular superoxide dismutase, Fe-SOD, Fe-SODe, Fe-SOD_ASAC, Fe-superoxide dismutase, Fe-type SOD, Fe/Mn-SOD, Fe/Mn-type SOD, Fe/MnSOD, ferrisuperoxide dismutase, FeSOD, GTNG_2884, hEC-SOD, hemocuprein, hepatocuprein, high isoelectric point superoxide dismutase, intracellular Cu-Zn superoxide dismutase, iron SOD, iron SOD type, iron superoxide dismutase, iron-containing superoxide dismutase, iron-dependent superoxide dismutase, iron-superoxide dismutase, KmSod1p, LSOD, manganese superoxide dismutase, manganese-containing SOD, manganese-containing superoxide dismutase, MgMnSOD1, MgMnSOD2, mitMn-SOD, mitochondrial manganese superoxide dismutase, mMnSOD, Mn-containing superoxide dismutase, Mn-SOD, Mn-type SOD, Mn/Fe superoxide dismutase, MnSOD, MnSOD-2, MnSOD-3, MnSOD1, MnSOD47, More, mtMnSOD, mtSOD, nectarin I, neelaredoxin, Nlr, Of-cCu/ZnSOD, PASOD, perMn-SOD, pfSOD, PschSOD, PsSOD, PthipI-SODC, PthipI-SODC1, PthipI-SODC2, RmFeSOD, RsrSOD, SaCSD1, SaFe-SOD, sdB, SOD, SOD 1, SOD I, SOD-1, SOD-2, SOD-3, SOD-4, SOD1, SOD2, SOD3, SODA, SodB, SODB1, SODB2, SodC, SODF, SODI, SODII, SODIII, SODIV, SODS, SSO0316, superoxide dismutase, superoxide dismutase 1, superoxide dismutase I, superoxide dismutase II, superoxide dismutase [Cu-Zn]
ECTree
1.15.1.1 superoxide dismutaseAdvanced search results
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results (Source Tissue
Source Tissue on EC 1.15.1.1 - superoxide dismutase
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SOURCE TISSUE 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
SOURCE
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enzyme mRNA is only found in the inner zones of adrenal cortex, not the glomerulosa. Enzyme activity in the inner zone mitochondria is enhaced by corticotrophin and by a low-sodium diet, but suppressed by betamethasone
accumulation of sodA mRNA in conidia, semi-quantitative expression analysis
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germinated cyst, isoform MnSOD2 and low levels of isoform MnSOD1
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sampled at altitudes of 1420, 1590 and 1920 m a.s.l. almost all superoxide dismutase activity represents Cu/Zn superoxide dismutase, about 4-6% represents Mn superoxide dismutase. In samples from 1590 and 1920 m a.s.l., enzyme activity is lower
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changes in SOD activity in boar sperm during preservation at 16°C, overview
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dogs with unilateral testicular tumor or unilateral cryptorchid testis, and with or without Sertoli cell tumor, seminoma and/or Leydig cell tumor
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in rats with hepatic necrosis after treatment with tetrachlorcarbon
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the splice variant hipI-SODC1b is differentially expressed, being clearly expressed in cambial and xylem, but not phloem, regions
additional information
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isozyme profile, 4 constitutive isozymes, 3 cold-inducible isozymes, overview. The enzyme activity declines in the beginning of storage, that with cold treatment at 4°C rapidly increases. After 7 days, two Fe-Sod isozymes are still active, while the Mn-SOD are inactivated
propagation of the fungus in the Mus musculus macrophage cell line derived from a reticulum sarcoma, J774.1, ATCC TIB-67, the enzyme expression is upregulated during macrophage infection
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Cg-EcSOD-expressing hemocytes were seen in blood circulation, in connective tissues, and closely associated to endothelium blood vessels. Cg-EcSOD presents in its amino acid sequence a LPS-binding motif found in the endotoxin receptor CD14, the protein displays an affinity to Escherichia coli bacteria and to LPS and lipid A
real time quantitative PCR expression analysis of cytoplasmic Cu,Zn-SOD
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during the early stretching of soybean leaves, removing cytokines or growth factors can induce Fe-SOD mRNA accumulation. In contrast, Fe-SOD mRNA accumulation is normal during any other stage by removing cytokines or growth factors. Fe-SOD expression is related to whether the development stage is leaf expansion or not
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superoxide dismutase activity falls for the first 11 days after infection with smooth type Salmonella typhimurium, coinciding with the period of bacterial growth in the liver. Mild infection with Pseudomonas aeruginosa stimulates superoxide dismutase
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peritoneal macrophages exposed to He-Ne laser radiation. Changes in the activity of superoxide dismutase as well as the formation of nitric oxide and peroxynitrite depend to a large extent on the laser radiation dose. Activation of enzyme at low radiation doses is accompanied by nitric oxide level increase without changes in peroxynitrite. Enhanced laser radiation doses inhibit the enzyme
semi-quantitative expression analysis, the expression is down regulates in the mycelium phase
the higher SOD activity in the middle part of the shoots can scavenge the fast-producing reactive oxygen species because it is the most abundant cell-division region
the higher SOD activity in the middle part of the shoots can scavenge the fast-producing Rreactive oxygen species because it is the most abundant cell-division region
additional information
optimal conditions for growth of this organism are 82-92°C, pH 3.0-4.0
additional information
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optimal conditions for growth of this organism are 82-92°C, pH 3.0-4.0
additional information
tissue specific expression of SOD, no activity in gonad and mantle
additional information
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tissue specific expression of SOD, no activity in gonad and mantle
additional information
bamboo SODs show developmental and tissue-specific regulation, unique fast-growth phenotype of green bamboo
additional information
bamboo SODs show developmental and tissue-specific regulation, unique fast-growth phenotype of green bamboo
additional information
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quantitative determination of an isotopically enriched metalloenzyme containing two different metal isotopes, method development, overview
additional information
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MnSOD-2 is constitutively expressed, while synthesis of MnSOD-3 is inducible
additional information
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growth temperature range of the strain OS-77 is between 5°C and 40°C with its optimum growth temperature of 20°C, the growth pH range of the strain OS-77 is between pH 6.0 and pH 10.0 with optimum growth at pH 8.0, strain OS-77 shows salinity tolerance up to 7.5% w/v NaCl solution
additional information
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growth temperature range of the strain OS-77 is between 5°C and 40°C with its optimum growth temperature of 20°C, the growth pH range of the strain OS-77 is between pH 6.0 and pH 10.0 with optimum growth at pH 8.0, strain OS-77 shows salinity tolerance up to 7.5% w/v NaCl solution
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additional information
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SOD activity during storage at 4°C for 9 days in egg yolk and egg white, overview, no activity change during 6 days storage but between 6th and 9th day, it decreased significantly in egg yolk while remained low but unchanged in egg white
additional information
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measurement of serum and urinary PC-Cu,Zn-SOD concentrations after application of exogenous recombinant human isozyme to male and female humans, overview
additional information
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measurement of serum and urinary PC-SOD concentrations after application of exogenous recombinant human isozyme to male and female humans, overview
additional information
organs from eight-leaf growth stage, enzyme MgMnSOD1 expression pattern, overview
additional information
organs from eight-leaf growth stage, enzyme MgMnSOD1 expression pattern, overview
additional information
organs from eight-leaf growth stage, enzyme MgMnSOD2 expression pattern, overview
additional information
organs from eight-leaf growth stage, enzyme MgMnSOD2 expression pattern, overview
additional information
a constitutive mRNA expression of Of-cCu/ZnSOD with higher levels in blood, liver, heart, and brain is observed, no expresion in muscle
additional information
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a constitutive mRNA expression of Of-cCu/ZnSOD with higher levels in blood, liver, heart, and brain is observed, no expresion in muscle
additional information
the enzyme contains no N-terminal signal peptide. Tissue-specific semiquantitative PCR enzyme expression analysis, Pinctada fucata superoxide dismutase mRNA is abundantly expressed in hemocytes and gill and scarcely expressed in other tissues tested
additional information
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the enzyme contains no N-terminal signal peptide. Tissue-specific semiquantitative PCR enzyme expression analysis, Pinctada fucata superoxide dismutase mRNA is abundantly expressed in hemocytes and gill and scarcely expressed in other tissues tested
additional information
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semi-quantitative enzyme expression analysis in adult tissues shows that the pfSOD mRNA is abundantly expressed in hemocytes and gill and scarcely expressed in other tissues tested
additional information
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during different developmental stages of Pleurotus ostreatus, the highest expression levels of the Mn-SOD gene appears in the stage of mature fruit bodies, followed by young fruit bodies and vegetative mycelia. The expression of the Mn-SOD gene is developmentally regulated
additional information
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cultivation on bean seeds of Phaseolus vulgaris, root colonization and growth of wild-type and mutant strains, overview
additional information
gene sodB gene, encoding Fe-SOD, is expressed highly in logarithmic phase cells but is downregulated in stationaryphase cells, except when the medium is amended with FeCl3 suggesting that downregulation of Pseudomonas putida sodB in stationary phase cells is due to Fe2+ depletion in this phase of growth. Removal of Fe2+ by adding a Fe-chelator decreases the sodB transcript level, even in logarithmicphase cells
additional information
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overview: content of Cu,Zn-SOD and Mn-SOD in rat tissues
additional information
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the enzyme is secreted by many cellular lines and it is also released trough a calcium-dependent depolarization mechanism involving SNARE protein SNAP 25
additional information
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overview: content of Cu,Zn-SOD and Mn-SOD in rat tissues
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additional information
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overview: content of Cu,Zn-SOD and Mn-SOD in rat tissues
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additional information
the Fe-SOD gene is expressed at low levels in Rhodobacter capsulatus cells grown under anaerobic or semiaerobic conditions, but expression is strongly induced upon exposure of the bacteria to air
additional information
Sulfolobus solfataricus grows between 50°C and 87°C with an optimum growing temperature of 87°C, but it neither grows nor survives at 90°C
additional information
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Sulfolobus solfataricus grows between 50°C and 87°C with an optimum growing temperature of 87°C, but it neither grows nor survives at 90°C
additional information
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quantitative real-time PCR enzyme expresion analysis
additional information
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quantitative real-time PCR enzyme tissue expression analysis
additional information
constant expression in plerocercoid larvae and adult worms
additional information
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constant expression in plerocercoid larvae and adult worms
additional information
the enzyme expression is upregulated in the yeast phase
additional information
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the enzyme expression is upregulated in the yeast phase
