Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.17.1.4: xanthine dehydrogenase

This is an abbreviated version!
For detailed information about xanthine dehydrogenase, go to the full flat file.

Word Map on EC 1.17.1.4

Reaction

xanthine
+
NAD+
+
H2O
=
Urate
+
NADH
+
H+

Synonyms

AtXDH1, EC 1.1.1.204, EC 1.2.1.37, IAO1, More, NAD-xanthine dehydrogenase, PaoABC, Retinol dehydrogenase, Rosy locus protein, VvXDH, xanthine dehydrogenase, xanthine dehydrogenase-1, xanthine dehydrogenase-2, xanthine dehydrogenase/oxidase, xanthine oxidoreductase, xanthine-NAD oxidoreductase, xanthine/NAD+ oxidoreductase, xanthine:NAD+ oxidoreductase, XDH, XDH/XO, XDH1, XDH2, XdhC, XOR, YagR, YagS, YagT

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.1 With NAD+ or NADP+ as acceptor
                1.17.1.4 xanthine dehydrogenase

Temperature Stability

Temperature Stability on EC 1.17.1.4 - xanthine dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2
-
dehydrogenase type stable under anaerobic conditions
30
-
enhanced stability of immobilized enzyme preparation if N2 and hemoglobin is included, reaction of oxygen products causes instability of the working enzyme, half-life: 250-560 min, compared to immobilized enzyme without additions of about 145 min
38
-
dehydrogenase type unstable, change to oxidase type inhibited under anaerobic conditions
40
-
stable for 10 min, pH 8.5
51.6
O54050; O54051; Q9X7K2
t1/2 for the wild-type enzyme, pH 8.5, 30 min
55
-
stable below
60
-
conversion of dehydrogenase type D to oxidase type O
63
O54050; O54051; Q9X7K2
t1/2 for the mutant Split166 enzyme, pH 8.5, 30 min
63.2
O54050; O54051; Q9X7K2
t1/2 for the mutant Split178 enzyme, pH 8.5, 30 min
70
10 min, complete loss of activity