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1.17.1.5: nicotinate dehydrogenase

This is an abbreviated version!
For detailed information about nicotinate dehydrogenase, go to the full flat file.

Word Map on EC 1.17.1.5

Reaction

nicotinate
+
H2O
+
NADP+
=
6-Hydroxynicotinate
+
NADPH
+
H+

Synonyms

dehydrogenase, nicotinate, EC 1.5.1.13, NA hydroxylase, NAH, NahAB1B2, NDH, NdhL, NdhM, NdhS, nicotinate dehydrogenase, nicotinic acid hydroxylase, three-component NA hydroxylase, three-component nicotinic acid hydroxylase

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.1 With NAD+ or NADP+ as acceptor
                1.17.1.5 nicotinate dehydrogenase

Cofactor

Cofactor on EC 1.17.1.5 - nicotinate dehydrogenase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4Fe-4S-center
Bactopterin
benzyl viologen
-
can replace NADP+
flavin
-
primary electron acceptor, 1.5-2 mol tightly bound flavin per mol of enzyme
molybdenum cofactor
molybdopterin
NAD+
Pusillimonas sp. (ex Stolz et al. 2005)
-
-
NADP+
NADPH
phenazine methosulfate
-
phenazine methosulfate-requiring enzyme
additional information
-