1.17.1.5: nicotinate dehydrogenase

This is an abbreviated version!
For detailed information about nicotinate dehydrogenase, go to the full flat file.

Word Map on EC 1.17.1.5

1.17.1.5

testosteroni

comamonas

putida

6-hydroxynicotinate

eubacterium

barkeri

multi-subunit

t7-like

pastoris

surpass

molybdenum

chassis

3-cyanopyridine

pichia

Reaction

Synonyms

dehydrogenase, nicotinate, EC 1.5.1.13, NA hydroxylase, NAH, NahAB1B2, NDH, NdhL, NdhM, NdhS, nicotinate dehydrogenase, nicotinic acid hydroxylase, three-component NA hydroxylase, three-component nicotinic acid hydroxylase

ECTree

1 Oxidoreductases

1.17 Acting on CH or CH₂ groups

1.17.1 With NAD⁺ or NADP⁺ as acceptor

1.17.1.5 nicotinate dehydrogenase

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Results	in table
6	Activating Compound
1130	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
38	Cofactor
2	Crystallization (Commentary)
4	General Information
3	General Stability
22	Inhibitors
10	KM Value [mM]
5	Localization
2	Metals/Ions
25	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
29	Organism
2	Oxidation Stability
4	Pathway
11	pH Optimum
1	pH Range
3	pH Stability
4	Protein Variants
8	Purification (Commentary)
1	Reaction
9	Reaction Type
27	Reference
1	Renatured (Commentary)
2	Source Tissue
16	Specific Activity [micromol/min/mg]
3	Storage Stability
58	Substrates and Products (Substrate)
13	Subunits
25	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 1.17.1.5 - nicotinate dehydrogenase

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1,10-phenanthroline

Bacillus sp. (in: Bacteria)

1 mM, 30-50% inhibition

2,2'-dipyridyl

6-Hydroxynicotinate

inhibits effectively

Acriflavin

Pseudomonas fluorescens

1 mM, 10 min at 35°C, 22% loss of activity

644529

AgNO3

Pseudomonas fluorescens

1 mM, 10 min at 35°C, complete loss of activity

644529

Atabrine

Bacillus sp. (in: Bacteria)

1 mM, 30-50% inhibition

644530

CuCl2

Pseudomonas fluorescens

1 mM, 10 min at 35°C, complete loss of activity

644529

HgCl2

Pseudomonas fluorescens

1 mM, 10 min at 35°C, complete loss of activity

644529

KCN

3 entries

N-ethylmaleimide

Pseudomonas fluorescens

1 mM, 10 min at 35°C, complete loss of activity

644529

NaCl

Bacillus sp. (in: Bacteria)

sufficient NaCl inhibits enzyme activity significantly

644530

NaN3

Pseudomonas fluorescens

1 mM, 10 min at 35°C, 17% loss of activity

644529

p-chloromercuribenzoate

Pseudomonas fluorescens

1 mM, 10 min at 35°C, complete loss of activity

644529

phenylhydrazine

Pseudomonas fluorescens

1 mM, 10 min at 35°C, 15% loss of activity

644529

Selenophosphate

Eubacterium barkeri

7 mM, 30 min, anaerobic conditions, reversible complete inactivation, time-dependent

644535

sodium selenide

Eubacterium barkeri

7 mM, 10 min, anaerobic conditions, reversible complete inactivation, time-dependent

644535

Sulfide

2 entries

additional information

Eubacterium barkeri

not inhibited by incubation for 1 h at room temperature with 100 mM KCN

644535