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1.17.7.4: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

This is an abbreviated version!
For detailed information about 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, go to the full flat file.

Word Map on EC 1.17.7.4

Reaction

dimethylallyl diphosphate
+ 2 oxidized ferredoxin [iron-sulfur] cluster +
H2O
=
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
+ 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+

Synonyms

(E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1, 4-hydroxy-3-methylbut-2-enyl pyrophosphate reductase, BgHDR1, BgHDR2, chloroplast biogenesis6, Clb6, DsHDR, E-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, EC 1.17.1.2, HDR, HDR1, HMBPP reductase, HsHDR1, HsHDR2, isoprenoid synthesis H, ispH, lysis-tolerant B, LytB, reductase, (E)-4-hydroxy-3-methylbut-2-enyl diphosphate, SrHDR

ECTree

     1 Oxidoreductases
         1.17 Acting on CH or CH2 groups
             1.17.7 With an iron-sulfur protein as acceptor
                1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

Inhibitors

Inhibitors on EC 1.17.7.4 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(E)-4-amino-3-methylbut-2-en-1-yl diphosphate
-
-
(E)-4-mercapto-3-methyl-but-2-en-1-yl diphosphate
-
-
2-(pyridin-3-yl)ethyl diphosphate
-
i.e. BPH-1027
BPH-1029
-
-
BPH-293
-
-
but-3-ynyl diphosphate
-
-
Ca2+
-
inhibitory
Fe2+
-
inhibitory
Imidazol
-
-
Mg2+
-
inhibitory
Mn2+
-
inhibitory
N-methylpyridinium
-
-
Ni2+
-
inhibitory
propargyl alcohol
-
weak inhibition, binding structure, overview
propargyl diphosphate
pyridin-2-ylmethyl diphosphate
-
i.e. BPH-1029
pyridin-3-ylmethyl diphosphate
-
i.e. BPH-293
pyridin-4-ylmethyl trihydrogen diphosphate
-
i.e. BPH-1030
pyridine-N-oxide
-
-
Zn2+
-
complete inhibition
additional information
-