1.18.1.1: rubredoxin-NAD+ reductase
This is an abbreviated version!
For detailed information about rubredoxin-NAD+ reductase, go to the full flat file.
Word Map on EC 1.18.1.1
Reaction
Synonyms
(flavo)rubredoxin reductase, ABO_0162, dihydronicotinamide adenine dinucleotide-rubredoxin reductase, DPNH-rubredoxin reductase, EC 1.6.7.2, FIRd-reductase, NAD(P)H:rubredoxin reductase, NADH-rubredoxin oxidoreductase, NADH-rubredoxin reductase, NADH: rubredoxin oxidoreductase, NADH:rubredoxin oxidoreductase, NOR, NROR, RdxR, reduced nicotinamide adenine dinucleotide-rubredoxin reductase, reductase, rubredoxin-nicotinamide adenine dinucleotide, rubB, rubredoxin reductase, rubredoxin-NAD reductase
ECTree
1.18.1.1 rubredoxin-NAD+ reductaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.18.1.1 - rubredoxin-NAD+ reductase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2 ferricytochrome c + NADH
2 ferrocytochrome c + NAD+ + H+
-
weak activity
-
-
?
NADH + 2-methyl-1,4-naphthoquinone
NAD+ + 2-methyl-1,4-naphthoquinol
-
-
-
-
?
NADH + H+ + oxidized methyl thiazolyl tetrazolium
NAD+ + reduced methyl thiazolyl tetrazolium
NADH + nitroblue tetrazolium
NAD+ + reduced nitroblue tetrazolium
-
weak activity
-
-
?
NADH + p-iodonitrotetrazolium
NAD+ + reduced p-iodonitrotetrazolium
-
-
-
-
?
reduced Desulfovibrio gigas rubredoxin + NAD+ + H+
oxidized Desulfovibrio gigas rubredoxin + NADH
Megalodesulfovibrio gigas
-
-
-
-
r
NADH + 2,6-dichloroindophenol
NAD+ + reduced 2,6-dichloroindophenol
-
-
-
-
?
NADH + 2,6-dichloroindophenol
NAD+ + reduced 2,6-dichloroindophenol
-
-
-
-
?
NADH + 2,6-dichloroindophenol
NAD+ + reduced 2,6-dichloroindophenol
-
-
-
-
?
NADH + H+ + oxidized methyl thiazolyl tetrazolium
NAD+ + reduced methyl thiazolyl tetrazolium
-
-
-
?
NADH + H+ + oxidized methyl thiazolyl tetrazolium
NAD+ + reduced methyl thiazolyl tetrazolium
-
-
-
?
NADH + H+ + oxidized rubredoxin-2
NAD+ + reduced rubredoxin
i.e. AlkG. Isoform RubB can reduce AlkG, therefore compensating for the absence of AlkT, also a rubredoxin reductase, missing inAlcanivorax borkumensis SK2 genome
-
-
?
NADH + H+ + oxidized rubredoxin-2
NAD+ + reduced rubredoxin
i.e. AlkG. Isoform RubB can reduce AlkG, therefore compensating for the absence of AlkT, also a rubredoxin reductase, missing inAlcanivorax borkumensis SK2 genome
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
-
-
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
-
the induction of rubredoxin reductase, normally observed at pH 4.3 is stopped immediately after the addition of rifampicin. The enzyme could play a role in some deacidification mechanism in relation to proton transport
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
-
enzyme mediates electron transfer from NADH to Desulfovibrio gigas rubredoxin as well as to E. coli flavorubredoxin
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
Megalodesulfovibrio gigas
-
very specific towards Desulfovibrio gigas rubredoxin
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
-
enzyme catalyzes electron transfer not only to the rubredoxin of Pseudomonas oleovorans but also to the lower molecular weight rubredoxins of the anaerobic bacteria Peptostreptococcus elsdenii, Clostridium pasteurianum and Desulfovibrio gigas
-
-
?
NADH + oxidized rubredoxin
NAD+ + reduced rubredoxin
-
enzyme is required for fatty acid and alkane hydroxylation
-
-
?
reduced rubredoxin + NAD(P)+
oxidized rubredoxin + NAD(P)H
the enzyme and two rubredoxins form a system indipensable for metabolizing n-alkanes, they constitute an electron transport pathway that shuttles reducing equivalents from carbon metabolism to the membrane-bound alkane hydroxylases AlkB1 and AlkB2
-
-
?
reduced rubredoxin + NAD(P)+
oxidized rubredoxin + NAD(P)H
rubredoxin-rubredoxin reductase complex formation, only a small number of direct interactions govern mutual recognition of RdxR and Rdx, corroborating the transient nature of the complex, overview, substrate binding structure and mechanism, the enzyme discriminates between two types of rubredoxins, RubA2 and RubA1, overview
-
-
?
additional information
?
-
-
enzyme catalyzes rubredoxin-dependent reduction of cytochrome c in presence of NADH
-
-
?
additional information
?
-
Megalodesulfovibrio gigas
-
enzyme catalyzes rubredoxin-dependent reduction of cytochrome c in presence of NADH
-
-
?
additional information
?
-
-
no activity with spinach ferredoxin, putidaredoxin and adrenodoxin
-
-
?
additional information
?
-
-
diaphorase activity towards ferricyanide
-
-
?
additional information
?
-
-
both the nonphysiological 1Fe form of rubredoxin and the physiological 2 Fe form combine with rubredoxin reductase to form functional electron transfer complexes. The reductive half-reaction of the rubredoxin reductase occurs by a simple one-step mechanism in which oxidized enzyme is reduced to an enzyme-NAD+ charge-transfer species
-
-
?
additional information
?
-
-
enzyme catalyzes rubredoxin-dependent reduction of cytochrome c in presence of NADH
-
-
?
additional information
?
-
-
enzyme catalyzes rubredoxin-dependent reduction of cytochrome c in presence of NADH
-
-
?
additional information
?
-
-
enzyme catalyzes rubredoxin-dependent reduction of cytochrome c in presence of NADH
-
-
?
