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1.2.1.10: acetaldehyde dehydrogenase (acetylating)

This is an abbreviated version!
For detailed information about acetaldehyde dehydrogenase (acetylating), go to the full flat file.

Word Map on EC 1.2.1.10

Reaction

acetaldehyde
+
CoA
 +
NAD+
=
acetyl-CoA
 +
NADH
 +
H+

Synonyms

4-hydroxy-2-ketovalerate aldolase/acylating acetaldehyde dehydrogenase, ACDH, acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating], acetaldehyde-alcohol dehydrogenase, acetyl-CoA reductase, acylating acetaldehyde dehydrogenase, AdhE, ADHES77, aldehyde dehydrogenase, aldehyde dehydrogenase (acylating), aldehyde/alcohol dehydrogenase, ALDH, BAD, bi-functional alcohol/aldehyde dehydrogenase, bifunctional acetaldehyde-alcohol dehydrogenase, BphJ, CoA-acylating aldehyde dehydrogenase, CoA-dependent aldehyde dehydrogenase, coenzyme A linked aldehyde dehydrogenase, coenzyme A-acylating aldehyde dehydrogenase, DmpF, DmpFG, MhpF, More, NAD+/CoA-dependent aldehyde dehydrogenase, nonphosphorylating acylating aldehyde dehydrogenase, PduP, Teth514_0627, Teth514_1942, Tsac_0416, TTHB247

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.10 acetaldehyde dehydrogenase (acetylating)

Molecular Weight

Molecular Weight on EC 1.2.1.10 - acetaldehyde dehydrogenase (acetylating)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
120000
-
one of four isozymes, gel filtration
140000
-
-
148000
-
gel filtration, molecular mass of enzyme complex, occurs in complex with 4-hydroxy-2-ketovalerate
180000 - 440000
dimeric-tetrameric enzyme, native PAGE
188000
-
gel filtration
265000
gel filtration
290000
-
gel filtration and sedimentation coefficient
32500
-
2 * 32500 + 2 * 39000, determined by nucleotide sequence, SDS-PAGE, two subunits of aldehyde dehydrogenase (acylating) and two of 4-hydroxy-2-ketovalerate
33344
-
1 * 33344, electrospray ionization mass spectrometry
35300
-
gel filtration
360000
-
gel filtration
370000
-
one of four isozymes, gel filtration
39000
-
2 * 32500 + 2 * 39000, determined by nucleotide sequence, SDS-PAGE, two subunits of aldehyde dehydrogenase (acylating) and two of 4-hydroxy-2-ketovalerate
400000
48000
-
4 * 48000, SDS-PAGE
51700
5 * 51700, calculated, 5 * 52400, SDS-PAGE
520000
-
one of four isozymes, gel filtration
52400
5 * 51700, calculated, 5 * 52400, SDS-PAGE
55000
-
2 * 55000, SDS-PAGE
555000
gel filtration
85000
x * 85000, SDS-PAGE
900000
-
one of four isozymes, gel filtration
94900
6 * 97700, calculated, 6 * 94900, SDS-PAGE
95000
-
x * 95000, SDS-PAGE, amino acid sequence
96000
96600
deduced from sequence
97700
6 * 97700, calculated, 6 * 94900, SDS-PAGE