1.2.1.27: methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
This is an abbreviated version!
For detailed information about methylmalonate-semialdehyde dehydrogenase (CoA-acylating), go to the full flat file.
Word Map on EC 1.2.1.27
-
1.2.1.27
-
lysosomotropic
-
3-hydroxyisobutyrate
-
coa-dependent
-
mississippi
-
propionyl-coa
-
aldh6a1
-
3-hydroxypropionic
- 1.2.1.27
-
lysosomotropic
- 3-hydroxyisobutyrate
-
coa-dependent
-
mississippi
- propionyl-coa
- aldh6a1
-
3-hydroxypropionic
Reaction
Synonyms
Aldh6a1, dddC, FG99_15390, KES23460, malonate-semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase, methylmalonate semialdehyde dehydrogenase protein, methylmalonate-semialdehyde dehydrogenase, methylmalonic acid semialdehyde dehydrogenase, MGG_01606, MMSADH, MMSDH, MoMSDH, MSDH, NAD-dependent malonate-semialdehyde dehydrogenase, OdoMMSDH, OsALDH6, PA3570, SSO1218
ECTree
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)Advanced search results
results (
results (Reference
top
Reference on EC 1.2.1.27 - methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Goodwin, G.W.; Rougraff, P.M.; Davis, E.J.; Harris, R.A.
Purification and characterization of methylmalonate-semialdehyde dehydrogenase from rat liver. Identity to malonate-semialdehyde dehydrogenase
J. Biol. Chem.
264
14965-14971
1989
Rattus norvegicus
Hatter, K.; Sokatch, J.R.
Purification of methylmalonate-semialdehyde dehydrogenase from Pseudomonas aeruginosa PAO
Methods Enzymol.
166
389-393
1988
Homo sapiens, Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO
Bannerjee, D.; Sanders, L.E.; Sokatch, J.R.
Properties of purified methylmalonate semialdehyde dehydrogenase of Pseudomonas aeruginosa
J. Biol. Chem.
245
1828-1835
1970
Pseudomonas aeruginosa
Sokatch, J.R.; Sanders, L.E.; Marshall, V.P.
Oxidation of methylmalonate semialdehyde to propionyl coenzyme A in Pseudomonas aeruginosa grown on valine
J. Biol. Chem.
243
2500-2506
1968
Pseudomonas aeruginosa
Harris, R.A.; Popov, K.M.; Kedishvili, N.Y.; Zhao, Y.; Shimomura, Y.; Robbins, B.; Crabb, D.W.
Molecular cloning of the branched-chain.alpha-keto acid dehydrogenase kinase and the CoA-dependent methylmalonate semialdehyde dehydrogenase
Adv. Enzyme Regul.
33
255-265
1993
Rattus norvegicus
Zhang, Y.X.; Tang, L.; Hutchinson, C.R.
Cloning and characterization of a gene (msdA) encoding methylmalonic acid semialdehyde dehydrogenase from Streptomyces coelicolor
J. Bacteriol.
178
490-495
1996
Streptomyces coelicolor
Kedishvili, N.Y.; Goodwin, G.W.; Popov, K.M.; Harris, R.A.
Mammalian methylmalonate-semialdehyde dehydrogenase
Methods Enzymol.
324
207-218
2000
Homo sapiens, Rattus norvegicus
Dubourg, H.; Stines-Chaumeil, C.; Didierjean, C.; Talfournier, F.; Rahuel-Clermont, S.; Branlant, G.; Aubry, A.
Expression, purification, crystallization and preliminary X-ray diffraction data of methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis
Acta Crystallogr. Sect. D
60
1435-1437
2004
Bacillus subtilis
Oguchi, K.; Tanaka, N.; Komatsu, S.; Akao, S.
Methylmalonate-semialdehyde dehydrogenase is induced in auxin-stimulated and zinc-stimulated root formation in rice
Plant Cell Rep.
22
848-858
2004
Oryza sativa (O49218), Oryza sativa
Stines-Chaumeil, C.; Talfournier, F.; Branlant, G.
Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis
Biochem. J.
395
107-115
2006
Bacillus subtilis
Li, C.; Akopiants, K.; Reynolds, K.A.
Identification and disruptional analysis of the Streptomyces cinnamonensis msdA gene, encoding methylmalonic acid semialdehyde dehydrogenase
J. Ind. Microbiol. Biotechnol.
33
75-83
2006
Streptomyces virginiae
Tanaka, N.; Takahashi, H.; Kitano, H.; Matsuoka, M.; Akao, S.; Uchimiya, H.; Komatsu, S.
Proteome approach to characterize the methylmalonate-semialdehyde dehydrogenase that is regulated by gibberellin
J. Proteome Res.
4
1575-1582
2005
Oryza sativa, Oryza sativa Japonica
Gao, C.; Han, B.
Evolutionary and expression study of the aldehyde dehydrogenase (ALDH) gene superfamily in rice (Oryza sativa)
Gene
431
86-94
2009
Oryza sativa (Q6Z4E4)
Su, H.C.; Ramkissoon, K.; Doolittle, J.; Clark, M.; Khatun, J.; Secrest, A.; Wolfgang, M.C.; Giddings, M.C.
The development of ciprofloxacin resistance in Pseudomonas aeruginosa involves multiple response stages and multiple proteins
Antimicrob. Agents Chemother.
54
4626-4635
2010
Pseudomonas aeruginosa
Esser, D.; Kouril, T.; Talfournier, F.; Polkowska, J.; Schrader, T.; Bräsen, C.; Siebers, B.
Unraveling the function of paralogs of the aldehyde dehydrogenase super family from Sulfolobus solfataricus
Extremophiles
17
205-216
2013
Saccharolobus solfataricus (Q97YT9), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q97YT9)
Talfournier, F.; Stines-Chaumeil, C.; Branlant, G.
Methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis: substrate specificity and coenzyme A binding
J. Biol. Chem.
286
21971-21981
2011
Bacillus subtilis
Bchini, R.; Dubourg-Gerecke, H.; Rahuel-Clermont, S.; Aubry, A.; Branlant, G.; Didierjean, C.; Talfournier, F.
Adenine binding mode is a key factor in triggering the early release of NADH in coenzyme A-dependent methylmalonate semialdehyde dehydrogenase
J. Biol. Chem.
287
31095-31103
2012
Bacillus subtilis (P42412), Bacillus subtilis
Sass, J.O.; Walter, M.; Shield, J.P.; Atherton, A.M.; Garg, U.; Scott, D.; Woods, C.G.; Smith, L.D.
3-Hydroxyisobutyrate aciduria and mutations in the ALDH6A1 gene coding for methylmalonate semialdehyde dehydrogenase
J. Inherit. Metab. Dis.
35
437-442
2012
Homo sapiens (Q02252), Homo sapiens
Wilding, M.; Scott, C.; Peat, T.S.; Newman, J.
X-ray crystal structure of a malonate-semialdehyde dehydrogenase from Pseudomonas sp. strain AAC
Acta Crystallogr. Sect. F
73
24-28
2017
Pseudomonas sp., Pseudomonas sp. AAC
Do, H.; Lee, C.W.; Lee, S.G.; Kang, H.; Park, C.M.; Kim, H.J.; Park, H.; Park, H.; Lee, J.H.
Crystal structure and modeling of the tetrahedral intermediate state of methylmalonate-semialdehyde dehydrogenase (MMSDH) from Oceanimonas doudoroffii
J. Microbiol.
54
114-121
2016
Oceanimonas doudoroffii (G5CZI2), Oceanimonas doudoroffii, Oceanimonas doudoroffii ATCC 27123 (G5CZI2)
Norvienyeku, J.; Zhong, Z.; Lin, L.; Dang, X.; Chen, M.; Lin, X.; Zhang, H.; Anjago, W.M.; Lin, L.; Abdul, W.; Wang, Z.
Methylmalonate-semialdehyde dehydrogenase mediated metabolite homeostasis essentially regulate conidiation, polarized germination and pathogenesis in Magnaporthe oryzae
Environ. Microbiol.
19
4256-4277
2017
Pyricularia oryzae (G4MTY9), Pyricularia oryzae, Pyricularia oryzae FGSC 8958 (G4MTY9), Pyricularia oryzae ATCC MYA-4617 (G4MTY9)
html completed
