1.2.1.30: carboxylate reductase (NADP+)

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For detailed information about carboxylate reductase (NADP+), go to the full flat file.

Reaction

Synonyms

aromatic acid reductase, aryl aldehyde:NADP+ oxidoreductase, aryl-aldehyde dehydrogenase (NADP+), aryl-aldehyde oxidoreductase, ATP/NADPH-dependent carboxylic acid reductase, CAR, carboxylate reductase, carboxylate reductases, Carboxylic acid reductase, kaCAR, mab3CAR, maCAR, mmCAR, mpCAR, msCAR, naCAR, NcCAR, niCAR, noCAR, tpCAR, type I CAR, type III CAR

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.1 With NAD⁺ or NADP⁺ as acceptor

                1.2.1.30 carboxylate reductase (NADP+)

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Results	in table
11	Activating Compound
9	AA Sequence
37	Application
1	CAS Registry Number
22	Cloned(Commentary)
81	Cofactor
93	General Information
1	General Stability
43	Inhibitors
84	kcat/KM [mM/s]
6	Ki Value [mM]
100	KM Value [mM]
25	Metals/Ions
6	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
75	Organism
3	PDB ID
14	pH Optimum
1	pH Range
1	pI Value
22	Posttranslational Modification
84	Protein Variants
12	Purification (Commentary)
36	Reaction
3	Reaction Type
61	Reference
4	Source Tissue
11	Specific Activity [micromol/min/mg]
5	Storage Stability
294	Substrates and Products (Substrate)
25	Subunits
137	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
1	Temperature Range [°C]
11	Temperature Stability [°C]
77	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.2.1.30 - carboxylate reductase (NADP+)

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

0°C, 2 weeks

Neurospora crassa

-

288182

0°C, in the presence of dithiothreitol, 2 months

Neurospora crassa

-

288183

0°C, plus reagents with SH-groups, 3 weeks

Neurospora crassa

-

288182

4°C, 50 mM Tris-HCl buffer, pH 7.5, 10% glycerol, 8 hours

Nocadia sp.

-

288184

pH 7.6, 50% glycerol, 1 mM EDTA, 2.5 mM mercaptoethanol, 6 months

Neurospora crassa

-

288180