1.2.1.65: salicylaldehyde dehydrogenase
This is an abbreviated version!
For detailed information about salicylaldehyde dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.65
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1.2.1.65
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salicylate
-
naphthalene
-
dioxygenase
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catechol
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1,2-dihydroxynaphthalene
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naphthalene-degrading
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phenanthrene
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cis,cis-muconic
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trans-o-hydroxybenzylidenepyruvate
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gentisate
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catechol-1,2-dioxygenase
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pyrene
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1-hydroxy-2-naphthoic
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o-phthalate
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1-naphthol
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2-hydroxymuconic
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1,2-dioxygenase
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carbaryl
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coal
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dihydrodiol
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environmental protection
- 1.2.1.65
- salicylate
- naphthalene
- dioxygenase
- catechol
- 1,2-dihydroxynaphthalene
-
naphthalene-degrading
- phenanthrene
-
cis,cis-muconic
- trans-o-hydroxybenzylidenepyruvate
- gentisate
-
catechol-1,2-dioxygenase
- pyrene
-
1-hydroxy-2-naphthoic
- o-phthalate
- 1-naphthol
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2-hydroxymuconic
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1,2-dioxygenase
- carbaryl
-
coal
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dihydrodiol
- environmental protection
Reaction
Synonyms
NAD+-dependent salicylaldehyde dehydrogenase, NahF, NahV, SAL dehydrogenase, SALD, SALDan, sALDH, salicylaldehyde dehydrogenase
ECTree
1.2.1.65 salicylaldehyde dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.2.1.65 - salicylaldehyde dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1-naphthaldehyde + NAD+ + H2O
1-naphthoate + NADH + 2 H+
-
low activity
-
-
?
2-carboxybenzaldehyde + NAD+ + H2O
2-carboxybenzoate + NADH + 2 H+
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very low activity
-
-
?
2-chlorobenzaldehyde + NAD+ + H2O
2-chlorobenzoate + NADH + 2 H+
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low activity
-
-
?
2-methoxybenzaldehyde + NAD+ + H2O
2-methoxybenzoate + NADH + 2 H+
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low activity
-
-
?
2-naphthaldehyde + NAD+ + H2O
2-naphthoate + NADH + 2 H+
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moderate activity
-
-
?
2-nitrobenzaldehyde + NAD+ + H2O
2-nitrobenzoate + NADH + 2 H+
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low activity
-
-
?
3-carboxybenzaldehyde + NAD+ + H2O
3-carboxybenzoate + NADH + 2 H+
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very low activity
-
-
?
3-chlorobenzaldehyde + NAD+ + H2O
3-chlorobenzoate + NADH + 2 H+
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moderate activity
-
-
?
3-hydroxybenzaldehyde + NAD+ + H2O
3-hydroxybenzoate + NADH + 2 H+
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low to moderate activity
-
-
?
3-methoxybenzaldehyde + NAD+ + H2O
3-methoxybenzoate + NADH + 2 H+
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moderate activity
-
-
?
3-nitrobenzaldehyde + NAD+ + H2O
3-nitrobenzoate + NADH + 2 H+
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low activity
-
-
?
4-carboxybenzaldehyde + NAD+ + H2O
4-carboxybenzoate + NADH + 2 H+
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very low activity
-
-
?
4-chlorobenzaldehyde + NAD+ + H2O
4-chlorobenzoate + NADH + 2 H+
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high activity
-
-
?
4-hydroxybenzaldehyde + NAD+ + H2O
4-hydroxybenzoate + NADH + 2 H+
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low activity
-
-
?
4-methoxybenzaldehyde + NAD+ + H2O
4-methoxybenzoate + NADH + 2 H+
-
low activity
-
-
?
4-nitrobenzaldehyde + NAD+ + H2O
4-nitrobenzoate + NADH + 2 H+
-
moderate activity
-
-
?
glutaraldehyde + NAD+ + H2O
glutarate + NADH + 2 H+
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very low activity
-
-
?
isovaleraldehyde + NAD+ + H2O
isovalerate + NADH + 2 H+
-
very low activity
-
-
?
m-nitrobenzaldehyde + NAD+ + H2O
m-nitrobenzoate + NADH + H+
-
-
-
?
o-nitrobenzaldehyde + NAD+ + H2O
o-nitrobenzoate + NADH + H+
-
-
-
?
propionaldehyde + NAD+ + H2O
propionate + NADH + 2 H+
-
very low activity
-
-
?
5-chlorosalicylaldehyde + NAD+ + H2O
5-chlorosalicylate + NADH + H+
-
-
-
?
5-chlorosalicylaldehyde + NAD+ + H2O
5-chlorosalicylate + NADH + H+
-
-
-
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + 2 H+
-
moderate to high activity
-
-
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + 2 H+
highest substrate specificity for benzaldehyde
-
-
?
benzaldehyde + NAD+ + H2O
benzoate + NADH + 2 H+
highest substrate specificity for benzaldehyde
-
-
?
caprylic aldehyde + NAD+ + H2O
caprylic acid + NADH + H+
-
-
-
?
caprylic aldehyde + NAD+ + H2O
caprylic acid + NADH + H+
-
-
-
?
glutaraldehyde + NAD+ + H2O
glutarate + NADH + H+
-
-
-
?
o-methoxybenzaldehyde + NAD+ + H2O
o-methoxybenzoate + NADH + H+
-
-
-
?
o-methoxybenzaldehyde + NAD+ + H2O
o-methoxybenzoate + NADH + H+
-
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH
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intermediate in the degradation pathway of naphthalene to catechol
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH
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intermediate in the degradation pathway of naphthalene to catechol
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH
-
intermediate in the degradation pathway of naphthalene to catechol
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH
-
intermediate in the degradation pathway of naphthalene to catechol
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
-
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
amino acids Asn149 and Glu250 may bind salicylaldehyde
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
-
conversion of salicylaldehyde to salicylate in Pseudomonas putida ND6 is mediated by two isofunctional, inducible, plasmid-encoded enzymes, NahF and NahV
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
-
conversion of salicylaldehyde to salicylate in Pseudomonas putida ND6 is mediated by two isofunctional, inducible, plasmid-encoded enzymes, NahF and NahV
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
second highest substrate specificity for benzaldehyde
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + 2 H+
second highest substrate specificity for benzaldehyde
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + H+
best substrate
-
-
?
salicylaldehyde + NAD+ + H2O
salicylate + NADH + H+
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activity assay
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-
?
additional information
?
-
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nah operon in Pseudomonas putida, which is present on the 83 kb metabolic plasmid NAH7 includes nahF gene coding for salicylaldehyde dehydrogenase
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-
?
additional information
?
-
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nahV mRNA levels are 3fold lower than the nahF mRNA levels in the wild-type ND6 strain
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-
?
additional information
?
-
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nah operon in Pseudomonas putida, which is present on the 83 kb metabolic plasmid NAH7 includes nahF gene coding for salicylaldehyde dehydrogenase
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-
?
additional information
?
-
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nahV mRNA levels are 3fold lower than the nahF mRNA levels in the wild-type ND6 strain
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-
?
additional information
?
-
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the enzyme shows maximum activity on salicylaldehyde and very poor activity on aliphatic aldehydes. The preferences of substrate (derivatives of benzaldehyde) for enzyme SALDH are dependent on nature, position and group of substituents. Enzyme SALDH prefers: (1) hydroxyl derivative at ortho and meta position, (2) chloro and nitro derivative at meta and para position, and (3) methoxy at meta position. The carboxyl group substitution is poorly preferred. Enzyme SALDH also shows activity on di-aromatic aldehydes. Substrate specificity, overview
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-
?
additional information
?
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the enzyme's salicylaldehyde dehydrogenase specific activity is higher than its aldehyde dehydrogenase specific activity
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-
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additional information
?
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the enzyme's salicylaldehyde dehydrogenase specific activity is higher than its aldehyde dehydrogenase specific activity
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-
-
additional information
?
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the enzyme's salicylaldehyde dehydrogenase specific activity is higher than its aldehyde dehydrogenase specific activity
-
-
-
additional information
?
-
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the enzyme's salicylaldehyde dehydrogenase specific activity is higher than its aldehyde dehydrogenase specific activity
-
-
-
additional information
?
-
-
involved in the degradation of acenaphthylene
-
-
?
