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1.2.1.75: malonyl-CoA reductase (malonate semialdehyde-forming)

This is an abbreviated version!
For detailed information about malonyl-CoA reductase (malonate semialdehyde-forming), go to the full flat file.

Reaction

malonate semialdehyde
+
CoA
+
NADP+
=
malonyl-CoA
+
NADPH
+
H+

Synonyms

bi-functional malonyl-CoA reductase, malonate semialdehyde reductase, malonate-semialdehyde dehydrogenase, malonyl CoA reductase (malonate semialdehyde-forming), malonyl-CoA reductase, MCR, More, MSAR

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)

Expression

Expression on EC 1.2.1.75 - malonyl-CoA reductase (malonate semialdehyde-forming)

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
extracts of autotrophically grown cells exhibit an NADPH-dependent succinyl-CoA reductase activity of 200 nM/min*mg of soluble protein, whereas extracts of heterotrophically grown cells exhibit an activity of 10 nM/min*mg of protein
-
in heterotropically grown cells, activity is downregulated to 40 nmol per min and mg
-
under autotrophic conditions, 10fold upregulation
-