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1.2.1.84: alcohol-forming fatty acyl-CoA reductase

This is an abbreviated version!
For detailed information about alcohol-forming fatty acyl-CoA reductase, go to the full flat file.

Word Map on EC 1.2.1.84

Reaction

a long-chain acyl-CoA
+ 2 NADPH + 2 H+ =
a long-chain alcohol
 + 2 NADP+ +
CoA

Synonyms

alcohol-forming FAR, alcohol-forming fatty acyl-CoA reductase, CER4, CG1443, FACR, FAR, FAR1, FAR10, FAR11, FAR12, FAR13, FAR14, FAR15, FAR16, FAR17, FAR2, FAR3, FAR4, FAR5, FAR6, FAR7, FAR8, FAR9, fatty acyl coenzyme A reductase, fatty acyl-CoA reductase, fatty acyl-CoA reductase 1, fatty acyl-CoA reductase 3, fatty acyl-CoA:NADPH oxidoreductase (long chain alcohol forming), fatty acyl-Coenzyme A reductase, FcrA, intestinal acyl-CoA reductase, male sterility C-terminal domain, male sterility domain-containing protein 1, Maqu_2220, Maqu_2507, Ms25, peroxisomal fatty acyl-CoA reductase 1, PsFAR I, PsFAR II, RS30405, wat, Waterproof

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.84 alcohol-forming fatty acyl-CoA reductase

Cloned

Cloned on EC 1.2.1.84 - alcohol-forming fatty acyl-CoA reductase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli BL21 cells
-
expressed in Escherichia coli JM109 cells and Saccharomyces cerevisiae
expressed in Lipomyces starkeyi strain NRRL Y-11557
-
expressed in Rhodococcus opacus strain PD630
Marinobacter nauticus
expressed in Saccharomyces cerevisiae
expressed in Saccharomyces cerevisiae strain BY4741
expressed in Saccharomyces cerevisiae, Brachypodium distachyon, Arabidopsis thaliana, Nicotiana benthamiana and Solanum lycopersicum
-
expressed in Saccharomyces cerevisiae, Solanum lycopersicum and Oryza sativa
expressed in Solanum lycopersicum, Arabidopsis thaliana and yeast
expressed in Solanum lycopersicum, Arabidopsis thaliana, and yeast
expressed in Spodoptera frugiperda Sf9 and High Five insect cells
-
expressed in Spodoptera frugiperda Sf9 insect cells
-
expressed in Yarrowia lipolytica and Saccharomyces cerevisiae
expression in Escherichia coli
expression in HEK 293 cells
expression using baculoviral system
gene FAR, recombinant expression in Saccharomyces cerevisiae wild-type strain BY4742 and in quadruple mutant strain H1246 lacking genes involved in triacylglycerolsand sterol esters synthesis
gene far, recombinant expression of EGFP-tagged or FLAG-tagged wild-type and diverse truncation mutants of FAR in CHO-K1 cells, construction and expresion of several chimeric FAR1-FAR2 constructs in CHO-K1 cells, overview. Recombinant expression of N- and C-terminally HA-tagged Far1 in CHO-K1 and ZPEG251 cells
gene maqu_2220, recombinant expression in Escherichia coli leading to fatty alcohol production, coexpression with gene fadD in Escherichia coli strain BL21DELTAfadE
Marinobacter nauticus
gene maqu_2507, recombinant expression in Escherichia coli leading to fatty alcohol production, coexpression with gene fadD in Escherichia coli strain BL21DELTAfadE
Marinobacter nauticus
gene PsFAR I, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic tree, quantitative real-time PCR enzyme expression analysis
gene PsFAR II, DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic tree, quantitative real-time PCR enzyme expression analysis
gene wat, recombinant expression in Saccharomyces cerevisiae strain H1246, recombinant expression of the enzyme and the peroxisomal marker mRFP-SKL in Drosophila S2 cells