1.2.1.88: L-glutamate gamma-semialdehyde dehydrogenase

This is an abbreviated version!
For detailed information about L-glutamate gamma-semialdehyde dehydrogenase, go to the full flat file.

Word Map on EC 1.2.1.88

1.2.1.88

ornithine

prodhs

putas

l-proline

hyperprolinemia

1.5.1.12

delta-1-pyrroline-5-carboxylate

medicine

agriculture

Reaction

Synonyms

1-pyrroline dehydrogenase, aldehyde dehydrogenase 12, ALDH12, Aldh4a1, dehydrogenase, 1-pyrroline-5-carboxylate, DELTA1-pyrroline-5-carboxylate dehydrogenase, delta1-pyrroline-5-carboxylate synthetase, DR_0813, EC 1.5.1.12, GSAL dehydrogenase, GSALDH, l-glutamate-gamma-semialdehyde dehydrogenase, L-pyrroline-5-carboxylate-NAD+ oxidoreductase, LRRP Ba1-651, NAD+-dependent glutamate gamma-semialdehyde dehydrogenase, OsALDH12, OsALDH18-2, P5C dehydrogenase, P5C synthase, P5C-DH, P5CD, P5CDH, P5CDH1, P5CS, PDH, PpALDH12, proline/P5C dehydrogenase, Put2, PutA, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylate synthase, pyrroline-5-carboxylic acid dehydrogenase, Tc00.1047053510943.50, YcgN, ZmALDH12

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase

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Results	in table
2	Activating Compound
27445	AA Sequence
3	Application
1	CAS Registry Number
17	Cloned(Commentary)
43	Cofactor
10	Crystallization (Commentary)
30	Disease/ Diagnostics
5	Expression
12	General Information
4	General Stability
8	IC50 Value
146	Inhibitors
23	kcat/KM [mM/s]
24	Ki Value [mM]
79	KM Value [mM]
23	Localization
2	Metals/Ions
31	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
122	Organism
8	Pathway
65	PDB ID
17	pH Optimum
5	pH Range
1	pI Value
26	Protein Variants
14	Purification (Commentary)
8	Reaction
4	Reaction Type
73	Reference
52	Source Tissue
28	Specific Activity [micromol/min/mg]
5	Storage Stability
109	Substrates and Products (Substrate)
27	Subunits
67	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
7	Temperature Stability [°C]
35	Turnover Number [1/s]

KM Value

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KM Value on EC 1.2.1.88 - L-glutamate gamma-semialdehyde dehydrogenase

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0.037 - 2

1-pyrroline-5-carboxylate

21 entries

0.173 - 0.211

2-aminoadipic semialdehyde

2 entries

0.5

3-Methoxybenzaldehyde

Hyalomma dromedarii

isoform A

392065

0.25

4-methoxybenzaldehyde

isoform A

acetaldehyde

isoform A

0.5

benzaldehyde

Hyalomma dromedarii

isoform A

392065

0.133

D-glucose

Hyalomma dromedarii

isoform A

392065

1.86

D-glyceraldehyde 3-phosphate

Zea mays

A0A2H4PMI3

pH 7.5, 30°C, recombinant wild-type enzyme

763363

0.76

formaldehyde

Hyalomma dromedarii

isoform A

392065

0.032 - 0.48

Glutaric semialdehyde

7 entries

glyoxylic acid

Hyalomma dromedarii

isoform A

392065

0.2

indol-3-acetaldehyde

Hyalomma dromedarii

isoform A

392065

0.12 - 97

L-glutamate 5-semialdehyde

9 entries

0.02 - 103

NAD+

16 entries

0.0095 - 3.066

NADP+

9 entries

0.27

p-nitrobenzaldehyde

Hyalomma dromedarii

isoform A

392065

additional information

5 entries