1.2.1.95: L-2-aminoadipate reductase

This is an abbreviated version!
For detailed information about L-2-aminoadipate reductase, go to the full flat file.

Word Map on EC 1.2.1.95

1.2.1.95

albicans

schizosaccharomyces

saccharopine

pombe

chrysogenum

phosphopantetheinylate

l-lysine

homoisocitrate

homocitrate

isofunctional

lysine-supplemented

pptases

Reaction

L-2-aminoadipyl-[LYS2 peptidyl-carrier-protein]

Synonyms

AAR, AarA, AasS, alpha-AAR, alpha-aminoadipate delta-semialdehyde synthase, alpha-aminoadipate reductase, L-alpha-aminoadipic acid reductase, Lys1+, LYS2, Nps3

ECTree

1 Oxidoreductases

1.2 Acting on the aldehyde or oxo group of donors

1.2.1 With NAD⁺ or NADP⁺ as acceptor

1.2.1.95 L-2-aminoadipate reductase

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Results	in table
1	Activating Compound
1274	AA Sequence
2	Application
7	Cloned(Commentary)
5	Cofactor
3	Expression
5	General Information
5	Inhibitors
4	kcat/KM [mM/s]
1	Ki Value [mM]
11	KM Value [mM]
4	Metals/Ions
6	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
17	Organism
3	Pathway
1	pH Optimum
1	pH Range
3	Posttranslational Modification
73	Protein Variants
2	Purification (Commentary)
3	Reaction
17	Reference
1	Source Tissue
2	Storage Stability
13	Substrates and Products (Substrate)
4	Subunits
25	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
5	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.2.1.95 - L-2-aminoadipate reductase

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(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate

L-2-aminoadipate + NADPH + H+ + ATP

Candida albicans

Q12572

presence of ATP and Mg2+ required

656800

adipate + NADPH + H+ + ATP

adipate semialdehyde + NADP+ + AMP + diphosphate

Saccharomyces cerevisiae

P07702

288201

D-2-aminoadipate + NADPH + H+ + ATP

(R)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate

Saccharomyces cerevisiae

P07702

288201

L-2-aminoadipate + NADPH + H+ + ATP

(S)-2-amino-6-oxohexanoate + NADP+ + AMP + diphosphate

5 entries

S-carboxymethyl-L-cysteine + NADPH + H+ + ATP

? + NADP+ + AMP + diphosphate

Penicillium chrysogenum

20fold lower activity than with L-2-aminoadipate

656194

S-carboxymethyl-L-cysteine + NADPH + H+ + ATP

S-formylmethyl-L-cysteine + NADP+ + AMP + diphosphate

Saccharomyces cerevisiae

P07702

288201

additional information

2 entries