1.2.7.8: indolepyruvate ferredoxin oxidoreductase

This is an abbreviated version!
For detailed information about indolepyruvate ferredoxin oxidoreductase, go to the full flat file.

Reaction

Synonyms

3-(indol-3-yl)pyruvate synthase (ferredoxin), arylpyruvate-ferredoxin oxidoreductase, hydroxyphenylpyruvate oxidase, indolepyruvate oxidase, indolepyruvate-ferredoxin oxidoreductase, indolepyruvate:Fd oxidoreductase, IOR, phenylpyruvate oxidase, VOR

ECTree

     1 Oxidoreductases

         1.2 Acting on the aldehyde or oxo group of donors

             1.2.7 With an iron-sulfur protein as acceptor

                1.2.7.8 indolepyruvate ferredoxin oxidoreductase

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Results	in table
3	Activating Compound
10137	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
2	Cofactor
1	Expression
1	General Information
1	General Stability
5	Inhibitors
1	Ki Value [mM]
18	KM Value [mM]
1	Localization
18	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
44	Organism
5	Oxidation Stability
4	Pathway
2	pH Optimum
1	pH Stability
7	Purification (Commentary)
1	Reaction
1	Reaction Type
14	Reference
6	Specific Activity [micromol/min/mg]
41	Substrates and Products (Substrate)
13	Subunits
14	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
4	Temperature Range [°C]
4	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.2.7.8 - indolepyruvate ferredoxin oxidoreductase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + 2 reduced ferredoxin + H+

Pyrococcus furiosus

-

-

639362, 644700

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

5 entries

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin + H+

2 entries

2-keto-4-methylthiobutyrate + CoA + oxidized ferredoxin

CO2 + reduced ferredoxin + 3-methylthiopropionyl-CoA

Pyrococcus furiosus

-

-

639362, 644700

-

-

r

2-ketoisocaproate + CoA + oxidized ferredoxin

CO2 + reduced ferredoxin + isovaleryl-CoA

Pyrococcus furiosus

-

-

639362, 644700

-

-

r

3-methyl-2-oxobutanoate + H2O + oxidized methyl viologen

S-(2-methylpropanoyl)-CoA + reduced methyl viologen + H+

Pyrococcus furiosus

-

-

745202

-

-

?

4-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

4-hydroxyphenylacetyl-CoA + CO2 + reduced ferredoxin + H+

Thermococcus profundus

-

-

725574

-

-

?

4-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

? + CO2 + reduced ferredoxin + H+

2 entries

indolepyruvate + CoA + oxidized methylviologen

indoleacetyl-CoA + CO2 + reduced methylviologen

4 entries

p-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

p-hydroxyphenylacetyl-CoA + CO2 + reduced ferredoxin

2 entries

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

5 entries

phenylpyruvate + CoA + oxidized methyl viologen

phenylacetyl-CoA + CO2 + reduced methyl viologen + H+

2 entries

additional information

?

-

2 entries

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

Methanothermobacter thermautotrophicus

-

-

639362, 644697

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

Methanothermobacter thermautotrophicus

-

biosynthesis of amino acids from fatty acids

644697

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

Pyrococcus furiosus

-

-

639362, 644700, 644703

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

Pyrococcus furiosus

-

involved in peptide fermentation and metabolism of aromatic amino acids

644700

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin

Thermococcus kodakarensis

-

-

644703

-

-

r

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin + H+

Thermococcus profundus

-

-

725574

-

-

?

(indol-3-yl)pyruvate + CoA + oxidized ferredoxin

S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin + H+

Thermococcus profundus DSM DT5432

-

-

725574

-

-

?

4-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

? + CO2 + reduced ferredoxin + H+

Thermococcus profundus

-

-

725574

-

-

?

4-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

? + CO2 + reduced ferredoxin + H+

Thermococcus profundus DSM DT5432

-

-

725574

-

-

?

indolepyruvate + CoA + oxidized methylviologen

indoleacetyl-CoA + CO2 + reduced methylviologen

Pyrococcus furiosus

-

-

639362, 644703

-

-

?

indolepyruvate + CoA + oxidized methylviologen

indoleacetyl-CoA + CO2 + reduced methylviologen

Thermococcus kodakarensis

-

-

644703

-

-

?

indolepyruvate + CoA + oxidized methylviologen

indoleacetyl-CoA + CO2 + reduced methylviologen

Thermococcus profundus

-

-

725574

-

-

?

indolepyruvate + CoA + oxidized methylviologen

indoleacetyl-CoA + CO2 + reduced methylviologen

Thermococcus profundus DSM DT5432

-

-

725574

-

-

?

p-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

p-hydroxyphenylacetyl-CoA + CO2 + reduced ferredoxin

Pyrococcus furiosus

-

-

639362, 644700, 644703

-

-

r

p-hydroxyphenylpyruvate + CoA + oxidized ferredoxin

p-hydroxyphenylacetyl-CoA + CO2 + reduced ferredoxin

Thermococcus kodakarensis

-

-

644703

-

-

r

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

Methanothermobacter thermautotrophicus

-

-

639362, 644697

-

-

r

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

Pyrococcus furiosus

-

-

639362, 644700, 644703

-

-

r

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

Thermococcus kodakarensis

-

-

644703

-

-

r

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

Thermococcus profundus

-

-

725574

-

-

?

phenylpyruvate + CoA + oxidized ferredoxin

phenylacetyl-CoA + CO2 + reduced ferredoxin

Thermococcus profundus DSM DT5432

-

-

725574

-

-

?

phenylpyruvate + CoA + oxidized methyl viologen

phenylacetyl-CoA + CO2 + reduced methyl viologen + H+

Thermococcus profundus

-

-

725574

-

-

?

phenylpyruvate + CoA + oxidized methyl viologen

phenylacetyl-CoA + CO2 + reduced methyl viologen + H+

Thermococcus profundus DSM DT5432

-

-

725574

-

-

?

additional information

?

-

Pyrococcus furiosus

-

pyruvate and transaminated forms of the amino acids aspartate, valine, glutamate and alanine, 2-ketobutyrate, oxalacetate, 2-ketoisovalerate, 2-ketoglutarate, 2-ketomalonate and phenylglyoxylate are not oxidized

644700

-

-

?

additional information

?

-

Pyrococcus furiosus

-

pyruvate, 2-ketoisovalerate, 2-ketoglutarate, 2 ketobutyrate, and phenylglyoxylate are no substrates

639362

-

-

?