1.20.4.2: methylarsonate reductase
This is an abbreviated version!
For detailed information about methylarsonate reductase, go to the full flat file.
Word Map on EC 1.20.4.2
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1.20.4.2
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arsenic
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omega-1
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dimethylarsinic
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age-at-onset
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thioltransferase
- 1.20.4.2
- arsenic
- omega-1
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dimethylarsinic
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age-at-onset
- thioltransferase
Reaction
Synonyms
EC 1.97.1.7, GSTO1, GSTO2, MMA(V) reductase, monomethylarsonic acid (MMA V) reductase/hGSTO1, More, reductase, methylarsonate
ECTree
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Engineering on EC 1.20.4.2 - methylarsonate reductase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
A140D
isoform GSTO2, natural polymorphism, no significant alteration in monomethylarsonate reductase activity
DELTAE155
isoform GSTO2, natural polymorphism, 90% increase in monomethylarsonate reductase activity
DELTAE155/E208K
isoform GSTO2, natural polymorphism, 100% increase in monomethylarsonate reductase activity, decrease in heat stability
E208K
isoform GSTO2, natural polymorphism, slight increase in monomethylarsonate reductase activity, decrease in heat stability
N142D
isoform GSTO2, natural polymorphism, no significant alteration in monomethylarsonate reductase activity
additional information
additional information
naturally occurring mutations S86C, A140D, E155del, A236V, and E208K significantly decrease enzyme activity
additional information
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naturally occurring mutations S86C, A140D, E155del, A236V, and E208K significantly decrease enzyme activity
