1.21.3.7: tetrahydrocannabinolic acid synthase

This is an abbreviated version!
For detailed information about tetrahydrocannabinolic acid synthase, go to the full flat file.

Reaction

Synonyms

DELA1-THCA synthase, DELTA1-tetrahydrocannabinolic acid synthase, DELTA9-tetrahydrocannabinolic acid synthase, tetrahydrocannabinolic acid synthase, tetrahydrocannabinolic acid-synthase, tetrahydrocannabinolic-acid synthase, THCA synthase, THCA-synthase, THCAS

ECTree

     1 Oxidoreductases

         1.21 Catalysing the reaction X-H + Y-H = X-Y

             1.21.3 With oxygen as acceptor

                1.21.3.7 tetrahydrocannabinolic acid synthase

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Results	in table
1	Activating Compound
3	AA Sequence
11	Cloned(Commentary)
8	Cofactor
2	Crystallization (Commentary)
1	Expression
2	General Information
3	Inhibitors
4	kcat/KM [mM/s]
7	KM Value [mM]
1	Localization
2	Metals/Ions
11	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
18	Organism
4	Pathway
1	pH Optimum
1	pI Value
5	Posttranslational Modification
10	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
9	Source Tissue
2	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
16	Subunits
37	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.21.3.7 - tetrahydrocannabinolic acid synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

12 entries

cannabinerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

-

719637

-

-

?

additional information

?

-

Cannabis sativa

-

cannabigerol and cannabinero are no substrates

719637

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

-

720263, 745424, 745428

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

-

719489

-

-

ir

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

Q8GTB6

-

718487, 744452

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

-

744452

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

Q8GTB6

-

744573, 744759, 745421, 745476

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

-

745476

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

Q8GTB6

-

746002

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

Q8GTB6

-

719821

-

-

ir

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

best substrate

719637

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

about 98% conversion rate in 24 h

718732

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa

-

maximum conversion rate of about 98% in 24 h

719343

-

-

?

cannabigerolate + O2

DELTA9-tetrahydrocannabinolate + H2O2

Cannabis sativa subsp. indica

-

-

745476

-

-

?