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1.21.99.3: thyroxine 5-deiodinase

This is an abbreviated version!
For detailed information about thyroxine 5-deiodinase, go to the full flat file.

Word Map on EC 1.21.99.3

Reaction

3,3',5'-triiodo-L-thyronine
+
Iodide
 +
acceptor
 +
H+
=
L-thyroxine
 +
reduced acceptor

Synonyms

5'-deiodinase, D3, deiodinase, deiodinase 3, deiodinase, thyroxine 5-, deiodinase-3, diiodothyronine 5'-deiodinase, Dio, Dio3, Dio3a, Dio3b, EC 1.97.1.11, ID-3, iodothyronine 5-deiodinase, iodothyronine deiodinase type III, iodothyronine inner ring monodeiodinase, iodothyronine monodeiodinase, ITHD, T4-5'-deiodinase, T4-5-deiodinase, thyroxine 5-deiodinase, type 3 deiodinase, type 3 iodothyronine 5-deiodinase, type 3 iodothyronine deiodinase, type III deiodinase, type III iodothyronine deiodinase, type-3 deiodinase, zD3

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.99 With unknown physiological acceptors
                1.21.99.3 thyroxine 5-deiodinase

KI Value

KI Value on EC 1.21.99.3 - thyroxine 5-deiodinase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00014 - 0.00017
4',4,6-trihydroxyaurone
4.8
6-Propyl-2-thiouracil
at 30°C, at pH 7.0, with 50 mM dithiothreitol
0.000005
N-bromoacetyl-3,3',5-triiodo-L-thyronine
additional information
additional information
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-
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