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1.21.99.4: thyroxine 5'-deiodinase

This is an abbreviated version!
For detailed information about thyroxine 5'-deiodinase, go to the full flat file.

Word Map on EC 1.21.99.4

Reaction

3,3',5-triiodo-L-thyronine
+
Iodide
+
acceptor
+
H+
=
L-thyroxine
+
reduced acceptor

Synonyms

5DI , 5DII , 5DIII , D1 5'-deiodinase, D2 5'-deiodinase, deiodinase, diiodothyronine 5'-deiodinase, Dio, DIO1, DIO2, DIOI , DIOII , DIOIII , EC 1.97.1.10, EC 3.8.1.4, ID-1, ID-2, ID-3, iodothyronine 5'-deiodinase, Iodothyronine 5'-monodeiodinase, iodothyronine 5-deiodinase, iodothyronine deiodinase 2, iodothyronine deiodinase D2, iodothyronine inner ring monodeiodinase, iodothyronine outer ring monodeiodinase, L-thyroxine iodohydrolase (reducing), thyroxine 5-deiodinase, Thyroxine deiodinase, type 1 5'-deiodinase, type 1 deiodinase, Type 1 DI , type 1 iodothyronine deiodinase, type 2 5'-deiodinase, type 2 deiodinase, Type 2 DI , type 2 iodothyronine deiodinase, type 3 deiodinase, Type 3 DI , type I iodothyronine 5'-deiodinase, type I iodothyronine deiodinase, type I-like deiodinase, type II iodothyronine deiodinase, type II-like deiodinase, Type-I 5'deiodinase , Type-II 5'deiodinase , Type-III 5'deiodinase , types 1 iodothyronine selenodeiodinase, types 2 iodothyronine selenodeiodinase, XL-15

ECTree

     1 Oxidoreductases
         1.21 Catalysing the reaction X-H + Y-H = X-Y
             1.21.99 With unknown physiological acceptors
                1.21.99.4 thyroxine 5'-deiodinase

Substrates Products

Substrates Products on EC 1.21.99.4 - thyroxine 5'-deiodinase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3,3',5'-triiodo-L-thyronine + AH2
3,3'-diiodo-L-thyronine + iodide + A + H+
show the reaction diagram
3,3',5'-triiodo-L-thyronine + AH2
3,3'-diiodothyronine + iodide + A + H+
show the reaction diagram
-
-
-
-
?
3,3',5'-triiodothyronine + AH2
3,3'-diiodothyronine + iodide + A + H+
show the reaction diagram
3,3',5,5'-tetraiodo-L-thyronine + AH2
?
show the reaction diagram
-
-
-
?
3,3',5-triiodo-L-thyronine sulfate + reduced electron acceptor
diiodothyronine + iodide + electron acceptor
show the reaction diagram
-
-
-
?
3,3',5-triiodothyronine + AH2
3,3'-diiodothyronine + iodide + A + H+
show the reaction diagram
3,3',5-triiodothyronine + AH2
3,5-diiodothyronine + iodide + A + H+
show the reaction diagram
-
-
-
-
?
3,3',5-triiodothyronine + AH2
diiodothyronine + iodide + A + H+
show the reaction diagram
rT3 ORD activity
-
-
?
3,5'-diiodo-L-thyronine + AH2
3-iodothyronine + iodide + A + H+
show the reaction diagram
-
-
-
-
?
3,5,3'-triiodo-L-thyronine + iodide + A + H+
L-thyroxine + AH2
show the reaction diagram
assay at pH 7.2
-
-
?
L-3,5',3'-triiodothyronine + AH2
L-3,3'-diiodothyronine + iodide + A + H+
show the reaction diagram
L-3,5'-diiodothyonine + AH2
L-3-iodothyronine + iodide + A + H+
show the reaction diagram
-
-
-
-
?
L-3,5'-diiodothyronine + AH2
L-3-iodothyronine + iodide + A + H+
show the reaction diagram
-
-
-
-
?
L-3,5,3',5'-tetraiodothyronine + AH2
L-3,5,3'-triiodothyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + AH2
3,3',5'-triiodo-L-thyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + AH2
3,3',5'-triiodothyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + AH2
3,3',5-triiodo-L-thyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + AH2
3,3',5-triiodothyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + AH2
3,5,3'-triiodo-L-thyronine + iodide + A + H+
show the reaction diagram
L-thyroxine + electron acceptor
3,3',5-triiodothyronine + iodide + reduced electron acceptor
show the reaction diagram
L-thyroxine + reduced acceptor
3,3',5-triiodo-L-thyronine + iodide + acceptor + H+
show the reaction diagram
reverse triiodothyronine + AH2
diiodothyronine + iodide + A + H+
show the reaction diagram
sulfated reverse triiodothyronine + AH2
diiodothyronine + iodide + A + H+ + ?
show the reaction diagram
-
-
-
-
?
additional information
?
-