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1.23.1.2: (+)-lariciresinol reductase

This is an abbreviated version!
For detailed information about (+)-lariciresinol reductase, go to the full flat file.

Reaction

(-)-secoisolariciresinol
+
NADP+
=
(+)-lariciresinol
+
NADPH
+
H+

Synonyms

(+)-lariciresinol reductase, (+)-pinoresinol-(+)-lariciresinol reductase, (+)-pinoresinol/(+)-lariciresinol reductase, bi-functional pinoresinol/lariciresinol reductase, bifunctional pinoresinol-lariciresinol reductase 2, LuPLR2, More, pinoresinol reductase, pinoresinol reductase 2, pinoresinol-lariciresinol reductase, pinoresinol-lariciresinol reductase-2, pinoresinol/lariciresinol reductase, PLR, PLR-La1, PLR-Lc1, PLR-Lu2, PLR-Tp2, PLR1, PLR2, PrR2, RR-pinoresinol-RR-lariciresinol reductase

ECTree

     1 Oxidoreductases
         1.23 Reducing C-O-C group as acceptor
             1.23.1 With NADH or NADPH as donor
                1.23.1.2 (+)-lariciresinol reductase

Reference

Reference on EC 1.23.1.2 - (+)-lariciresinol reductase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vassao, D.; Kim, S.; Milhollan, J.; Eichinger, D.; Davin, L.; Lewis, N.
A pinoresinol-lariciresinol reductase homologue from the creosote bush (Larrea tridentata) catalyzes the efficient in vitro conversion of p-coumaryl/coniferyl alcohol esters into the allylphenols chavicol/eugenol, but not the propenylphenols p-anol/isoeug
Arch. Biochem. Biophys.
465
209-218
2007
Forsythia x intermedia
Manually annotated by BRENDA team
Chu, A.; Dinkova, A.; Davin, L.B.; Bedgar, D.L.; Lewis, N.G.
Stereospecificity of (+)-pinoresinol and (+)-lariciresinol reductases from Forsythia intermedia
J. Biol. Chem.
268
27026-27033
1993
Forsythia x intermedia
Manually annotated by BRENDA team
Fujita, M.; Gang, D.R.; Davin, L.B.; Lewis, N.G.
Recombinant pinoresinol-lariciresinol reductases from western red cedar (Thuja plicata) catalyze opposite enantiospecific conversions
J. Biol. Chem.
274
618-627
1999
Thuja plicata
Manually annotated by BRENDA team
Xie, L.H.; Akao, T.; Hamasaki, K.; Deyama, T.; Hattori, M.
Biotransformation of pinoresinol diglucoside to mammalian lignans by human intestinal microflora, and isolation of Enterococcus faecalis strain PDG-1 responsible for the transformation of (+)-pinoresinol to (+)-lariciresinol
Chem. Pharm. Bull.
51
508-515
2003
Enterococcus faecalis, Enterococcus faecalis PDG-1
Manually annotated by BRENDA team
Dinkova-Kostova, A.T.; Gang, D.R.; Davin, L.B.; Bedgar, D.L.; Chu, A.; Lewis, N.G.
(+)-Pinoresinol/(+)-lariciresinol reductase from Forsythia intermedia. Protein purification, cDNA cloning, heterologous expression and comparison to isoflavone reductase
J. Biol. Chem.
271
29473-29482
1996
Forsythia x intermedia
Manually annotated by BRENDA team
Katayama, T.; Davin, L.B.; Lewis, N.G.
An extraordinary accumulation of (-)-pinoresinol in cell-free extracts of Forsythia intermedia: evidence for enantiospecific reduction of (+)-pinoresinol
Phytochemistry
31
3875-3881
1992
Forsythia x intermedia
Manually annotated by BRENDA team
von Heimendahl, C.B.; Schaefer, K.M.; Eklund, P.; Sjoeholm, R.; Schmidt, T.J.; Fuss, E.
Pinoresinol-lariciresinol reductases with different stereospecificity from Linum album and Linum usitatissimum
Phytochemistry
66
1254-1263
2005
Linum album (Q4R0I0)
Manually annotated by BRENDA team
Bayindir, U.; Alfermann, A.W.; Fuss, E.
Hinokinin biosynthesis in Linum corymbulosum Reichenb.
Plant J.
55
810-820
2008
Linum corymbulosum (B5KRH5)
Manually annotated by BRENDA team
Hemmati, S.; von Heimendahl, C.B.; Klaes, M.; Alfermann, A.W.; Schmidt, T.J.; Fuss, E.
Pinoresinol-lariciresinol reductases with opposite enantiospecificity determine the enantiomeric composition of lignans in the different organs of Linum usitatissimum L.
Planta Med.
76
928-934
2010
Linum usitatissimum (E6Y2X0)
Manually annotated by BRENDA team
Tamura, M.; Tsuji, Y.; Kusunose, T.; Okazawa, A.; Kamimura, N.; Mori, T.; Nakabayashi, R.; Hishiyama, S.; Fukuhara, Y.; Hara, H.; Sato-Izawa, K.; Muranaka, T.; Saito, K.; Katayama, Y.; Fukuda, M.; Masai, E.; Kajita, S.
Successful expression of a novel bacterial gene for pinoresinol reductase and its effect on lignan biosynthesis in transgenic Arabidopsis thaliana
Appl. Microbiol. Biotechnol.
98
8165-8177
2014
Sphingobium sp. SYK-6 (G2IMF2)
Manually annotated by BRENDA team
Zhao, Q.; Zeng, Y.; Yin, Y.; Pu, Y.; Jackson, L.A.; Engle, N.L.; Martin, M.Z.; Tschaplinski, T.J.; Ding, S.Y.; Ragauskas, A.J.; Dixon, R.A.
Pinoresinol reductase 1 impacts lignin distribution during secondary cell wall biosynthesis in Arabidopsis
Phytochemistry
112
170-178
2015
Arabidopsis thaliana (Q9SVP6)
Manually annotated by BRENDA team
Corbin, C.; Drouet, S.; Mateljak, I.; Markulin, L.; Decourtil, C.; Renouard, S.; Lopez, T.; Doussot, J.; Lamblin, F.; Auguin, D.; Laine, E.; Fuss, E.; Hano, C.
Functional characterization of the pinoresinol-lariciresinol reductase-2 gene reveals its roles in yatein biosynthesis and flax defense response
Planta
246
405-420
2017
Linum usitatissimum (E6Y2X0)
Manually annotated by BRENDA team