1.3.1.102: 2-alkenal reductase (NADP+)
This is an abbreviated version!
For detailed information about 2-alkenal reductase (NADP+), go to the full flat file.
Word Map on EC 1.3.1.102
Reaction
Synonyms
2-alkenal reductase, 2-alkenal reductase (NADP+-dependent), AER, alkenal double bond reductase, allyl-ADH, allyl-ADH1, allyl-ADH2, allyl-alcohol dehydrogenase, AOR, AtAOR, chloroplastic alkenal/one oxidoreductase, double-bond reductase 1, double-bond reductase 2, NADPH-dependent alkenal/one oxidoreductase, NtDBR, NtRed-1, PaDBR1, PaDBR2
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1.3.1.102 2-alkenal reductase (NADP+)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.3.1.102 - 2-alkenal reductase (NADP+)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(1R,2S,4S)-neoisodihydrocarveol + NADP+
(1R,4S)-isodihydrocarvone + NADPH + H+
-
-
-
r
(2E)-3-methylpent-2-enal + NADPH + H+
2-methylpentanal + NADP+
-
-
-
?
(R)-pulegone + NADPH + H+
(1R,4R)-isomenthone + (1R,4S)-menthone + NADP+
-
-
-
?
(S)-pulegone + NADPH + H+
(1S,4S)-isomenthone + (1S,4R)-menthone + NADP+
-
-
-
?
1-cyclohexene-1-carboxaldehyde + NADPH + H+
cyclohexanecarbaldehyde + NADP+
low yields
-
-
?
4-coumaryl aldehyde + NADP+
dihydro-4-coumaryl aldehyde + NADPH + H+
-
-
-
?
caffeoyl aldehyde + NADP+
dihydrocaffeoyl aldehyde + NADPH + H+
-
-
-
?
[(1E)-1-nitroprop-1-en-2-yl]benzene + NADPH + H+
[(2R)-1-nitropropan-2-yl]benzene + NADP+
optically pure form of compound
-
-
?
[(1Z)-1-nitroprop-1-en-2-yl]benzene + NADPH + H+
[(2S)-1-nitropropan-2-yl]benzene + NADP+
poor enantioselectivity
-
-
?
5-hydroxyconiferyl aldehyde + NADP+
dihydro-5-hydroxyconiferyl aldehyde + NADPH + H+
-
-
-
?
5-hydroxyconiferyl aldehyde + NADP+
dihydro-5-hydroxyconiferyl aldehyde + NADPH + H+
only enzyme mutant PaDBR1C56Y, no activity with the wild-type enzyme
-
-
?
coniferyl aldehyde + NADP+
dihydroconiferyl aldehyde + NADPH + H+
-
-
-
?
coniferyl aldehyde + NADP+
dihydroconiferyl aldehyde + NADPH + H+
only enzyme mutant PaDBR1C56Y, no activity with the wild-type enzyme
-
-
?
additional information
?
-
enzyme AOR shows acrolein-reducing activity in addition to the cytosolic acrolein detoxification enzyme in leaves of higher plants
-
-
?
additional information
?
-
-
enzyme AOR shows acrolein-reducing activity in addition to the cytosolic acrolein detoxification enzyme in leaves of higher plants
-
-
?
additional information
?
-
-
2-alkenal reductase (AER) catalyzes the reduction of the alpha,beta-unsaturated bond of 2-alkenals to produce n-alkanals
-
-
?
additional information
?
-
recombinant NtRed-1 does not catalyze dehydrogenation of (2S,4S)-carveol, indicating that the recombinant NtRed-1 lacks the catalytic function as allyl-alcohol dehydrogenase, although the recombinant NtRed-1 is designed from the nucleotide sequence of allyl-ADH
-
-
?
additional information
?
-
results indicate that the enzyme catalyzes specifically the dehydrogenation of the secondary alcohols adjacent to the C-C double bond, no oxidation of saturated alcohols
-
-
?
additional information
?
-
the enzymatic reaction is a reversible oxidoreduction and the reaction is enantioselective
-
-
?
additional information
?
-
the recombinant isozyme PaDBR2 has a higher catalytic activity than isozyme PaDBR1 with respect to the reduction of the double bond present in hydroxycinnamyl aldehydes
-
-
?
additional information
?
-
the recombinant isozyme PaDBR2 has a higher catalytic activity than isozyme PaDBR1 with respect to the reduction of the double bond present in hydroxycinnamyl aldehydes
-
-
?
additional information
?
-
-
the recombinant isozyme PaDBR2 has a higher catalytic activity than isozyme PaDBR1 with respect to the reduction of the double bond present in hydroxycinnamyl aldehydes
-
-
?
additional information
?
-
docking of the ligand and substrate into the active cavity, overview. The catalytic efficiency of isozyme PaDBR1 is substantially less than that of PaDBR2, especially towards cinnamyl aldehydes carrying a methoxy group (coniferyl, 5-hydroxyconiferyl and sinapyl aldehydes). No activity with sinapyl aldehyde, cinnamyl aldehyde, 4-coumaric acid, caffeic acid, 4-coumaryl alcohol, caffeyl alcohol, coniferyl alcohol, 5-hydroxyconiferyl alcohol, and sinapyl alcohol
-
-
?
additional information
?
-
docking of the ligand and substrate into the active cavity, overview. The catalytic efficiency of isozyme PaDBR1 is substantially less than that of PaDBR2, especially towards cinnamyl aldehydes carrying a methoxy group (coniferyl, 5-hydroxyconiferyl and sinapyl aldehydes). No activity with sinapyl aldehyde, cinnamyl aldehyde, 4-coumaric acid, caffeic acid, 4-coumaryl alcohol, caffeyl alcohol, coniferyl alcohol, 5-hydroxyconiferyl alcohol, and sinapyl alcohol
-
-
?
additional information
?
-
-
docking of the ligand and substrate into the active cavity, overview. The catalytic efficiency of isozyme PaDBR1 is substantially less than that of PaDBR2, especially towards cinnamyl aldehydes carrying a methoxy group (coniferyl, 5-hydroxyconiferyl and sinapyl aldehydes). No activity with sinapyl aldehyde, cinnamyl aldehyde, 4-coumaric acid, caffeic acid, 4-coumaryl alcohol, caffeyl alcohol, coniferyl alcohol, 5-hydroxyconiferyl alcohol, and sinapyl alcohol
-
-
?
