1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)
This is an abbreviated version!
For detailed information about trans-2-enoyl-CoA reductase (NADPH), go to the full flat file.
Word Map on EC 1.3.1.38
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1.3.1.38
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beta-ketoacyl-coa
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beta-hydroxyacyl-coa
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dehydrase
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palmitoyl-coa
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butyryl-coa
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condensing
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vlcfas
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nadph-specific
- 1.3.1.38
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beta-ketoacyl-coa
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beta-hydroxyacyl-coa
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dehydrase
- palmitoyl-coa
- butyryl-coa
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condensing
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vlcfas
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nadph-specific
Reaction
Synonyms
2-trans enoyl-ACP(CoA) reductase, ECR, EgTER1, enoyl reductase, InhA, MECR, MECR-1, mitochondrial 2-trans-enoyl-CoA/ACP reductase, mitochondrial 2-trans-enoyl-thioester reductase, NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, TER, trans-2-enoyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH)
ECTree
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)Advanced search results
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results (Substrates Products
Substrates Products on EC 1.3.1.38 - trans-2-enoyl-CoA reductase (NADPH)
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-dodecenoyl-acyl carrier protein + NADH
dodecanoyl-acyl carrier protein + NAD+
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-
-
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?
2-trans,4-trans-decadienoyl-CoA + NADPH + H+
(4E)-dec-4-enoyl-CoA + NADP+
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-
-
-
?
nervonyl-CoA + NADPH
tetracosanoyl-CoA + NADP+
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-
1% of the activity with trans-phytenoyl-CoA
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ir
crotonyl-CoA + NADPH
butanoyl-CoA + NADP+
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i.e. trans-2-butenoyl-CoA
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?
trans-2-decenoyl-CoA + NADPH
decanoyl-CoA + NADP+
highest activity with, native and recombinant enzyme
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?
trans-2-hexenoyl-CoA + NADPH
hexanoyl-CoA + NADP+
50% activity compared to that with trans-2-decenoyl-CoA, native and recombinant enzyme
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?
trans-2-octenoyl-CoA + NADPH
octanoyl-CoA + NADP+
50% activity compared to that with trans-2-decenoyl-CoA, native and recombinant enzyme
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?
additional information
?
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key enzyme in fatty acid chain elongation pathway
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-
?
additional information
?
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key enzyme in fatty acid chain elongation pathway
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-
?
additional information
?
-
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no reduction of trans-2-tetradecenoyl-CoA
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-
?
additional information
?
-
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activity decreases with increasing chain length of substrates
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-
?
additional information
?
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-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
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-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
-
NADPH-specific trans-enoyl-CoA reductases from rat liver miochondria and microsomes impossible to classify according to EC 1.3.1.8 or EC 1.3.1.38 because no cis-isomers of 2-enoyl-CoA have been tested as substrates
-
-
?
additional information
?
-
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the enzyme directly binds with and enhances peroxisome proliferator-activated receptor alpha activity
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-
?
