1.3.1.39: enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)

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For detailed information about enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific), go to the full flat file.

Reaction

Synonyms

acyl-ACP dehydrogenase, enoyl-ACP reductase, enoyl-ACP reductase III, enoyl-[acyl carrier protein] (reduced nicotinamide adenine dinucleotide phosphate) reductase, FabI, FabK, FabL, NADPH 2-enoyl Co A reductase, PG1416

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)

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Results	in table
1288	AA Sequence
2	Application
1	CAS Registry Number
2	Cloned(Commentary)
6	Cofactor
2	Crystallization (Commentary)
5	IC50 Value
7	Inhibitors
3	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
12	Organism
9	Pathway
60	PDB ID
1	pH Stability
1	Reaction
3	Reaction Type
10	Reference
5	Source Tissue
3	Storage Stability
9	Substrates and Products (Substrate)
2	Subunits
14	Synonyms
1	Systematic Name

Inhibitors

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Inhibitors on EC 1.3.1.39 - enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

panosialin A

Staphylococcus aureus

Q6GI75

acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis

725690

panosialin B

Staphylococcus aureus

Q6GI75

acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis

725690

panosialin wA

Staphylococcus aureus

Q6GI75

acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis

725690

panosialin wB

Staphylococcus aureus

Q6GI75

acylbenzenediol sulfate metabolites from Streptomyces sp. AN1761, potently inhibits bacterial enoyl-ACP reductases of Staphylococcus aureus, Streptococcus pneumoniae, and Mycobacterium tuberculosis

725690

pyridoxal 5'-phosphate

Gallus gallus

-

4 mM at 30°C for 15 min on complete fatty acid synthase selectively and completely inactivates

390763

triclosan

2 entries

triclosan

Staphylococcus aureus

Q6GI75

-

725690

triclosan

Staphylococcus aureus

Q6GI75

affinity varies with pH-value

726455