1.3.1.56: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
This is an abbreviated version!
For detailed information about cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase, go to the full flat file.
Word Map on EC 1.3.1.56
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1.3.1.56
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biphenyls
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dioxygenase
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polychlorinated
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testosteroni
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comamonas
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pnomenusa
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burkholderia
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pandoraea
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chlorinated
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chlorobiphenyls
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congener
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dehydrogenation
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toluene
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bpha1a2a3a4
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cis-dihydrodiols
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cepacia
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meta-cleavage
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dehydrogenases
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ortho-substituted
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putida
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2,2\',5,5\'-tetrachlorobiphenyl
- 1.3.1.56
- biphenyls
- dioxygenase
-
polychlorinated
- testosteroni
-
comamonas
- pnomenusa
-
burkholderia
-
pandoraea
-
chlorinated
-
chlorobiphenyls
-
congener
-
dehydrogenation
- toluene
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bpha1a2a3a4
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cis-dihydrodiols
- cepacia
-
meta-cleavage
- dehydrogenases
-
ortho-substituted
- putida
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2,2\',5,5\'-tetrachlorobiphenyl
Reaction
Synonyms
2,3-dihydro-2,3-dehydroxybiphenyl-2,3-dehydrogenase, 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase, 2,3-dihydroxy-4-phenylhexa-4,6-diene dehydrogenase, B2,3D, BephB, biphenyl dehydrogenase, biphenyl dihydrodiol dehydrogenase, Biphenyl-2,3-dihydro-2,3-diol dehydrogenase, biphenyl-2,3-dihydrodiol 2,3-dehydrogenase, biphenyl-2,3-dihydrodiol-2,3-dehydrogenase, Biphenyl-cis-diol dehydrogenase, BphB, BphBB-356, BphBB356, cis-2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase, cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase, More, NAD-dependent cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
ECTree
1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.3.1.56 - cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
7,2',3'-trihydroxy-8-methyl-2',3'-dihydro-isoflavone + NAD+
7,2',3'-trihydroxy-8-methylisoflavone + NADH
7,3',4'-trihydroxy-3',4'-dihydro-isoflavone + NAD+
7,3',4'-trihydroxyisoflavone + NADH
-
recombinant enzyme
-
-
?
7-hydroxy-8-methylisoflavone + 2 NAD+ + 2 H2O
7,2',3'-trihydroxy-8-methylisoflavone + 2 NADH + 2 H+
cis-1,2-dihydro-1,2-dihydroxynaphthalene + NAD+
? + NADH
-
-
?
cis-indole-2,3-dihydrodiol + NAD+
2,3-dihydroxyindole + NADH
-
isatin can be formed by spontaneously isomerization of 2,3-dihydroxyindole, which is formed from cis-indole-2,3-dihydrodiol catalyzed by BphB
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-
?
2,2',5,5'-tetrachlorobiphenyl + NAD+
2,2',5,5'-tetrachloro-3,4-dihydroxybiphenyl + NADH
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-
-
-
?
2,2',5,5'-tetrachlorobiphenyl + NAD+
2,2',5,5'-tetrachloro-3,4-dihydroxybiphenyl + NADH
-
-
-
-
?
2,2',5,5'-tetrachlorobiphenyl + NAD+
2,2',5,5'-tetrachloro-3,4-dihydroxybiphenyl + NADH
-
-
-
-
?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
-
-
?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
-
-
?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
-
?
3,4-dihydro-3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NAD+
3,4-dihydroxy-2,2',5,5'-tetrachlorobiphenyl + NADH
-
-
-
?
7,2',3'-trihydroxy-8-methyl-2',3'-dihydro-isoflavone + NAD+
7,2',3'-trihydroxy-8-methylisoflavone + NADH
-
recombinant enzyme
-
-
?
7,2',3'-trihydroxy-8-methyl-2',3'-dihydro-isoflavone + NAD+
7,2',3'-trihydroxy-8-methylisoflavone + NADH
-
recombinant enzyme
-
-
?
7-hydroxy-8-methylisoflavone + 2 NAD+ + 2 H2O
7,2',3'-trihydroxy-8-methylisoflavone + 2 NADH + 2 H+
-
2-step biotransformation in cooperation with biphenyl-2,3-dioxygenase, BphA, catalyzing the first step and BphB the second step, recombinant enzymes in Escherichia coli cells
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-
?
7-hydroxy-8-methylisoflavone + 2 NAD+ + 2 H2O
7,2',3'-trihydroxy-8-methylisoflavone + 2 NADH + 2 H+
-
2-step biotransformation in cooperation with biphenyl-2,3-dioxygenase, BphA, catalyzing the first step and BphB the second step, recombinant enzymes in Escherichia coli cells
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-
?
7-hydroxyisoflavone + 2 NAD+ + 2 H2O
7,3',4'-trihydroxyisoflavone + 2 NADH + 2 H+
-
2-step biotransformation in cooperation with biphenyl-2,3-dioxygenase, BphA, catalyzing the first step and BphB the second step, recombinant enzymes in Escherichia coli cells
-
-
?
7-hydroxyisoflavone + 2 NAD+ + 2 H2O
7,3',4'-trihydroxyisoflavone + 2 NADH + 2 H+
-
2-step biotransformation in cooperation with biphenyl-2,3-dioxygenase, BphA, catalyzing the first step and BphB the second step, recombinant enzymes in Escherichia coli cells
-
-
?
cis-2,3-dihydro-2,3-dihydroxy-4,4'-dichlorobiphenyl + NAD+
?
-
-
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
2,3-dihydroxybiphenyl + ?
-
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
2,3-dihydroxybiphenyl + ?
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polychlorobiphenyl catabolic pathway
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?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
2,3-dihydroxybiphenyl + ?
-
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + ?
2,3-dihydroxybiphenyl + ?
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polychlorobiphenyl catabolic pathway
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD(P)+
2,3-dihydroxybiphenyl + NAD(P)H
-
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD(P)+
2,3-dihydroxybiphenyl + NAD(P)H
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second step of the metabolic pathway for the bacterial degradation of biphenyl
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?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
2,3-dihydroxybiphenyl + NADH
-
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
2,3-dihydroxybiphenyl + NADH
-
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
2,3-dihydroxybiphenyl + NADH
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biphenyl degradation pathway
-
?
cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
2,3-dihydroxybiphenyl + NADH
biphenyl degradation pathway
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?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH
-
-
-
-
?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH
-
-
-
-
?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH
-
-
-
-
?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH + H+
-
-
-
-
?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH + H+
-
-
-
-
?
cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+
biphenyl-2,3-diol + NADH + H+
modeling studies indicate that the substrate is bound in a deep hydrophobic cleft close to the nicotinamide moiety of the NAD+ cofactor. These studies further suggest that Asn143 is a key determinant of substrate specificity
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-
?
additional information
?
-
-
biotransformation of natural and synthetic isoflavonoids by the recombinant enzyme, overview
-
-
?
additional information
?
-
-
enzyme catalyzes the second step in the biphenyl catabolic degradation pathway, substrate spectrum of the organism in vivo, overview
-
-
?
additional information
?
-
-
enzyme shows a broad substrate specificity
-
-
?
additional information
?
-
-
enzyme shows a broad substrate specificity
-
-
?
additional information
?
-
-
biotransformation of natural and synthetic isoflavonoids by the recombinant enzyme, overview
-
-
?
additional information
?
-
-
enzyme shows a broad substrate specificity
-
-
?
additional information
?
-
-
enzyme catalyzes the second step in the biphenyl catabolic degradation pathway, substrate spectrum of the organism in vivo, overview
-
-
?
additional information
?
-
-
enzyme shows a broad substrate specificity
-
-
?
additional information
?
-
-
enzyme catalyzes the second step in the biphenyl catabolic degradation pathway, substrate spectrum of the organism in vivo, overview
-
-
?
additional information
?
-
-
enzyme shows a broad substrate specificity
-
-
?
