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1.3.1.89: tRNA-dihydrouridine47 synthase [NAD(P)+]

This is an abbreviated version!
For detailed information about tRNA-dihydrouridine47 synthase [NAD(P)+], go to the full flat file.

Reaction

5,6-dihydrouracil47 in tRNA
+
NAD(P)+
=
uracil47 in tRNA
+
NAD(P)H
+
H+

Synonyms

Dus3p, tRNA-dihydrouridine synthase 3

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+]

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Resultsin table
3174AA Sequence
1General Information
1Natural Substrates/ Products (Substrates)
1Organism
1Reaction
1Reference
2Substrates and Products (Substrate)
2Synonyms
1Systematic Name

General Information

General Information on EC 1.3.1.89 - tRNA-dihydrouridine47 synthase [NAD(P)+]

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
formation of dihydrouridine in yeast cytoplasmic tRNAs is carried out by a family of four dihydrouridine synthases (Dus1p, Dus2p, Dus3p, and Dus4p), each acting at specific positions in tRNAs. Dus1p modifies U16 and U17, Dus2p modifies U20, Dus3p modifies U47, and Dus4p modifies U20a and U20b. These four proteins are responsible for all dihydrouridine modification of cytoplasmic tRNAs in yeast