1.3.1.91: tRNA-dihydrouridine20 synthase [NAD(P)+]
This is an abbreviated version!
For detailed information about tRNA-dihydrouridine20 synthase [NAD(P)+], go to the full flat file.
Word Map on EC 1.3.1.91
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1.3.1.91
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dsrnas
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thermus
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d-loops
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thermophilus
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flavin
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carcinogenesis
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dsrbd
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archaea
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trnaphe
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elbow
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l-shaped
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medicine
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synthase-2
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diagnostics
- 1.3.1.91
- dsrnas
-
thermus
-
d-loops
- thermophilus
- flavin
- carcinogenesis
-
dsrbd
- archaea
- trnaphe
-
elbow
-
l-shaped
- medicine
- synthase-2
- diagnostics
Reaction
Synonyms
dihydrouridine synthase, dihydrouridine synthase 2, dihydrouridine synthase C, Dus, DUS 2, DUS2, Dus2p, DusA, DusB, DusC, EcoDusC, hDUS2, HsDus2, SMM1, tRNA-dihydrouridine synthase 2, tRNA-dihydrouridine synthases
ECTree
1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]Advanced search results
results (
results (Substrates Products
Substrates Products on EC 1.3.1.91 - tRNA-dihydrouridine20 synthase [NAD(P)+]
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
uracil in bulk tRNA + NADPH + H+
5,6-dihydrouracil in bulk tRNA + NADP+
the enzyme exhibits a clear preference for NADPH compared to NADH
-
-
?
uracil in pre-tRNALeu + NAD(P)H + H+
5,6-dihydrouracil in pre-tRNALeu + NAD(P)+
-
-
-
?
uracil in pre-tRNATyr + NAD(P)H + H+
5,6-dihydrouracil in pre-tRNATyr + NAD(P)+
-
-
-
?
uracil20 in tRNA + NADH + H+
5,6-dihydrouracil20 in tRNA + NAD+
-
-
-
?
uracil20a in tRNA + NADH + H+
5,6-dihydrouracil20a in tRNA + NAD+
-
-
-
?
more the enzyme it is not able to synthetize uracil16 in tRNA
?
-
-
-
?
more the enzyme it is not able to synthetize uracil16 in tRNA
?
Mycoplasma capricolum subsp. capricolum ATCC 14323
-
-
-
?
uracil in bulk tRNA + NADH + H+
5,6-dihydrouracil in bulk tRNA + NAD+
the enzyme exhibits a clear preference for NADPH compared to NADH
-
-
?
uracil in bulk tRNA + NADH + H+
5,6-dihydrouracil in bulk tRNA + NAD+
Mycoplasma capricolum subsp. capricolum ATCC 14323
the enzyme exhibits a clear preference for NADPH compared to NADH
-
-
?
uracil in tRNA + NAD(P)H + H+
5,6-dihydrouracil in tRNA + NAD(P)+
-
-
-
?
uracil in tRNA + NAD(P)H + H+
5,6-dihydrouracil in tRNA + NAD(P)+
the enzyme is specific for the proR hydrogen of NADPH. Cys117 is very important for the reduction of tRNA
-
-
r
uracil17 in tRNA + NADPH + H+
5,6-dihydrouracil17 in tRNA + NADP+
-
-
-
?
uracil17 in tRNA + NADPH + H+
5,6-dihydrouracil17 in tRNA + NADP+
Mycoplasma capricolum subsp. capricolum ATCC 14323
-
-
-
?
uracil20 in tRNA + NAD(P)H + H+
5,6-dihydrouracil20 in tRNA + NAD(P)+
-
-
-
?
uracil20 in tRNA + NAD(P)H + H+
5,6-dihydrouracil20 in tRNA + NAD(P)+
the enzyme specifically modifies uracil20 in tRNA, e.g. tRNALeu(CAA) and tRNATyr
-
-
?
uracil20 in tRNA + NAD(P)H + H+
5,6-dihydrouracil20 in tRNA + NAD(P)+
e.g. tRNALeu(CAA) and tRNATyr
-
-
?
uracil20 in tRNA + NADPH + H+
5,6-dihydrouracil20 in tRNA + NADP+
-
-
-
?
uracil20 in tRNA + NADPH + H+
5,6-dihydrouracil20 in tRNA + NADP+
-
-
-
?
uracil20 in tRNA + NADPH + H+
5,6-dihydrouracil20 in tRNA + NADP+
Mycoplasma capricolum subsp. capricolum ATCC 14323
-
-
-
?
uracil20 in tRNA + NADPH + H+
5,6-dihydrouracil20 in tRNA + NADP+
-
-
-
-
?
uracil20a in tRNA + NADPH + H+
5,6-dihydrouracil20a in tRNA + NADP+
-
-
-
?
uracil20a in tRNA + NADPH + H+
5,6-dihydrouracil20a in tRNA + NADP+
Mycoplasma capricolum subsp. capricolum ATCC 14323
-
-
-
?
additional information
?
-
tRNA recognition mechanism, overview
-
-
?
additional information
?
-
no enzymatic activity ith tRNAAsp substrate
-
-
?
