1.3.7.1: 6-hydroxynicotinate reductase

This is an abbreviated version!
For detailed information about 6-hydroxynicotinate reductase, go to the full flat file.

Reaction

+ 2 H+

Synonyms

6-hydroxynicotinic reductase, 6-oxotetrahydronicotinate dehydrogenase, HNA reductase, reductase, 6-hydroxynicotinate

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.7 With an iron-sulfur protein as acceptor

1.3.7.1 6-hydroxynicotinate reductase

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Results	in table
3	Activating Compound
96	AA Sequence
1	CAS Registry Number
2	Cofactor
5	General Stability
2	KM Value [mM]
1	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
3	Organism
1	Oxidation Stability
3	Pathway
1	pH Optimum
1	pH Range
1	pH Stability
2	Purification (Commentary)
1	Reaction
3	Reaction Type
3	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
6	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Reference

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Reference on EC 1.3.7.1 - 6-hydroxynicotinate reductase

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391150

Holcenberg, J.S.; Tsai, L.

Nicotinic acid metabolism. IV. Ferredoxin-dependent reduction of 6-hydroxynicotinic acid to 6-oxo-1,4,5,6-tetrahydronicotinic acid

J. Biol. Chem.

244

1204-1211

1969

Clostridium sp.

5767303

391151

Kitts, C.L.; Lapointe, J.P.; Lam, V.T.; Ludwig, R.A.

Elucidation of the complete Azorhizobium nicotinate catabolism pathway

J. Bacteriol.

174

7791-7797

1992

Azorhizobium caulinodans

1447145

670692

Alhapel, A.; Darley, D.J.; Wagener, N.; Eckel, E.; Elsner, N.; Pierik, A.J.

Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri

Proc. Natl. Acad. Sci. USA

103

12341-12346

2006

Eubacterium barkeri

16894175