1.3.8.1: short-chain acyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about short-chain acyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

3-hydroxyacyl CoA reductase, ACADS, Acfer_0556, Acfer_1477, acyl-CoA dehydrogenase short chain, BCAD, BCD, bcd2, BcdAf, bSCAD, butyryl CoA dehydrogenase, butyryl coenzyme A dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, butyryl-CoA dehydrogenase/Etf complex, CD1054, dehydrogenase, butyryl coenzyme A, EC 1.3.2.1, EC 1.3.99.2, enoyl-coenzyme A reductase, ethylene reductase, HADHSC, non-dissociating bifurcating Etf-Bcd complex, SCAD, ScdA, short chain acyl-CoA dehydrogenase, short-chain 3-hydroxyacyl-CoA dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, short-chain acylCoA dehydrogenase, unsaturated acyl coenzyme A reductase

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.8 With a flavin as acceptor

                1.3.8.1 short-chain acyl-CoA dehydrogenase

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Results	in table
3	Activating Compound
7829	AA Sequence
11	Application
1	CAS Registry Number
25	Cloned(Commentary)
30	Cofactor
3	Crystallization (Commentary)
692	Disease/ Diagnostics
2	Expression
22	General Information
2	General Stability
37	Inhibitors
6	kcat/KM [mM/s]
4	Ki Value [mM]
78	KM Value [mM]
23	Localization
3	Metals/Ions
33	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
145	Organism
2	Oxidation Stability
19	Pathway
39	PDB ID
17	pH Optimum
9	pH Range
5	pH Stability
2	pI Value
2	Posttranslational Modification
47	Protein Variants
27	Purification (Commentary)
6	Reaction
3	Reaction Type
102	Reference
1	Renatured (Commentary)
48	Source Tissue
39	Specific Activity [micromol/min/mg]
10	Storage Stability
178	Substrates and Products (Substrate)
19	Subunits
83	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
42	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 1.3.8.1 - short-chain acyl-CoA dehydrogenase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-18°C, 30% ethylene glycol, 15 mM phosphate pH 8.0, 20% loss of activity within 1 year

Clostridium kluyveri

-

696519

-18°C, 50% ethylene glycol, 6 months, 80% activity after reconstitution with FAD

Megasphaera elsdenii

-

391260

-20°C, 10 mM KH2PO4, pH 8.0, 0.2 M NaCl, 50% glycerol, at least 3 months

Rattus norvegicus

-

391272

-20°C, at least 1 month

Rattus norvegicus

-

391282

-76°C

Bos taurus

-

391283

-80°C, phosphate buffer, pH 7.6, 20% glycerol

Homo sapiens

-

672003, 672004

4°C, 0.1 M potassium phosphate buffer, pH 7, 0.02% sodium azide, 96 h, CoA-free enzyme 75% activity, CoA-containing enzyme 100% activity

Megasphaera elsdenii

-

391280

4°C, in the presence of FAD and under anoxic conditions, 2-3 days, 50% loss of activity

Clostridium kluyveri

-

687430

short term: 4°C, 0.1 M potassium phosphate buffer, pH 7, 0.02% sodium azide or 0.002% chlorhexidine, long term: frozen in ammonium sulfate

Megasphaera elsdenii

-

391284